Quantification of intra-abdominal fat during controlled weight reduction: assessment using the water-suppressed breath-hold MRI technique
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
15046562
Knihovny.cz E-resources
- MeSH
- Abdomen anatomy & histology MeSH
- Cholesterol blood MeSH
- Exercise physiology MeSH
- Diet MeSH
- Diet Records MeSH
- Adult MeSH
- Weight Loss physiology MeSH
- Body Mass Index MeSH
- Insulin blood MeSH
- Blood Glucose analysis MeSH
- Humans MeSH
- Lipoproteins blood MeSH
- Magnetic Resonance Imaging methods MeSH
- Obesity pathology physiopathology therapy MeSH
- Image Processing, Computer-Assisted MeSH
- Waist-Hip Ratio MeSH
- Subcutaneous Tissue anatomy & histology MeSH
- Body Weight MeSH
- Triglycerides blood MeSH
- Adipose Tissue anatomy & histology MeSH
- Water chemistry MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Cholesterol MeSH
- Insulin MeSH
- Blood Glucose MeSH
- Lipoproteins MeSH
- Triglycerides MeSH
- Water MeSH
A group of 14 healthy female subjects was studied using MRI during 2 months of life-style intervention. A series of 21 water-suppressed images was used to determine the intra-abdominal fat volume before and after the controlled loss of weight. The average weight decrease was 8.2 %, but the average relative loss of visceral fat was 20.3 %, whereas subcutaneous fat decreased by 13.4 %. A small but significant increase of insulin sensitivity (decrease in fasting insulin and blood glucose) was observed, but no changes in lipoprotein parameters were demonstrated. There was a significant negative correlation (r=-0.633, p=0.028) between the relative abdominal fat decrease and the initial amount of subcutaneous fat.
