Levels of apolipoprotein A-II in cerebrospinal fluid in patients with neuroborreliosis are associated with lipophagocytosis
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
15058201
DOI
10.1007/bf02931523
Knihovny.cz E-zdroje
- MeSH
- apolipoprotein A-I mozkomíšní mok MeSH
- apolipoprotein A-II mozkomíšní mok MeSH
- dítě MeSH
- dospělí MeSH
- fagocytóza imunologie MeSH
- imunoglobulin A mozkomíšní mok MeSH
- imunoglobulin G mozkomíšní mok MeSH
- imunoglobulin M mozkomíšní mok MeSH
- lidé středního věku MeSH
- lidé MeSH
- lymfocyty imunologie MeSH
- lymská neuroborelióza mozkomíšní mok imunologie MeSH
- mladiství MeSH
- monocyty imunologie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- Check Tag
- dítě MeSH
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- apolipoprotein A-I MeSH
- apolipoprotein A-II MeSH
- imunoglobulin A MeSH
- imunoglobulin G MeSH
- imunoglobulin M MeSH
Levels of most of the examined proteins in cerebrospinal fluid (CSF) of 107 patients with neuroborreliosis were associated with cytological findings, the status of hematoencephalic barrier as evaluated by Qalb (cerebrospinal fluid to serum quotient) and the intrathecal synthesis of immunoglobulins. Cytological findings consisted of normal cytology, or both oligocytosis and pleocytosis of monocytes or lymphocytes. The lipophagic elements were present in 20% of samples. Concentrations of apolipoproteins A-I and A-II in the CSF were correlated with the concentration of albumin without regard to the CSF cytology. The levels of apolipoprotein B were increased only in samples with lymphocytic pleocytosis and Qalb > 7.4. The presence of lipophages in the CSF was significantly associated with the CSF concentration of apolipoprotein A-II.
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Analysis of cerebrospinal fluid cell populations with monoclonal antibodies
Cerebrospinal-fluid profile in neuroborreliosis and its diagnostic significance
