The histidine kinases CYTOKININ-INDEPENDENT1 and ARABIDOPSIS HISTIDINE KINASE2 and 3 regulate vascular tissue development in Arabidopsis shoots
Jazyk angličtina Země Anglie, Velká Británie Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
19622803
PubMed Central
PMC2729606
DOI
10.1105/tpc.109.066696
PII: tpc.109.066696
Knihovny.cz E-zdroje
- MeSH
- Arabidopsis enzymologie genetika růst a vývoj MeSH
- geneticky modifikované rostliny enzymologie genetika růst a vývoj MeSH
- histidinkinasa MeSH
- imunoblotting MeSH
- imunoprecipitace MeSH
- polymerázová řetězová reakce s reverzní transkripcí MeSH
- proteinkinasy genetika fyziologie MeSH
- proteiny huseníčku genetika fyziologie MeSH
- regulace genové exprese u rostlin genetika fyziologie MeSH
- výhonky rostlin enzymologie genetika růst a vývoj MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- AHK2 protein, Arabidopsis MeSH Prohlížeč
- AHK3 protein, Arabidopsis MeSH Prohlížeč
- CKI1 protein, Arabidopsis MeSH Prohlížeč
- histidinkinasa MeSH
- proteinkinasy MeSH
- proteiny huseníčku MeSH
The development and activity of the procambium and cambium, which ensure vascular tissue formation, is critical for overall plant architecture and growth. However, little is known about the molecular factors affecting the activity of vascular meristems and vascular tissue formation. Here, we show that the His kinase CYTOKININ-INDEPENDENT1 (CKI1) and the cytokinin receptors ARABIDOPSIS HISTIDINE KINASE2 (AHK2) and AHK3 are important regulators of vascular tissue development in Arabidopsis thaliana shoots. Genetic modifications of CKI1 activity in Arabidopsis cause dysfunction of the two-component signaling pathway and defects in procambial cell maintenance. CKI1 overexpression in protoplasts leads to cytokinin-independent activation of the two-component phosphorelay, and intracellular domains are responsible for the cytokinin-independent activity of CKI1. CKI1 expression is observed in vascular tissues of inflorescence stems, and CKI1 forms homodimers both in vitro and in planta. Loss-of-function ahk2 and ahk3 mutants and plants with reduced levels of endogenous cytokinins show defects in procambium proliferation and an absence of secondary growth. CKI1 overexpression partially rescues ahk2 ahk3 phenotypes in vascular tissue, while the negative mutation CKI1H405Q further accentuates mutant phenotypes. These results indicate that the cytokinin-independent activity of CKI1 and cytokinin-induced AHK2 and AHK3 are important for vascular bundle formation in Arabidopsis.
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