In vitro antibacterial and antifungal activity of salicylanilide benzoates

. 2012 ; 2012 () : 290628. [epub] 20120430

Jazyk angličtina Země Spojené státy americké Médium print-electronic

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid22666101

The resistance to antimicrobial agents brings a need of novel antimicrobial agents. We have synthesized and found the in vitro antibacterial activity of salicylanilide esters with benzoic acid (2-(phenylcarbamoyl)phenyl benzoates) in micromolar range. They were evaluated in vitro for the activity against eight fungal and eight bacterial species. All derivatives showed a significant antibacterial activity against Gram-positive strains with minimum inhibitory concentrations ≥ 0.98 μmol/L including methicillin-resistant Staphylococcus aureus strain. The most active compounds were 5-chloro-2-(3,4-dichlorophenylcarbamoyl)phenyl benzoate and 4-chloro-2-(4-(trifluoromethyl)phenylcarbamoyl)phenyl benzoate. The antifungal activity is significantly lower.

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Gould IM. Antibiotic resistance: the perfect storm. International Journal of Antimicrobial Agents. 2009;34(supplement 3):S2–S5. PubMed

Mielke M. Prevention and control of nosocomial infections and resistance to antibiotics in Europe—primum non-nocere: elements of successful prevention and control of healthcare-associated infections. International Journal of Medical Microbiology. 2010;300(6):346–350. PubMed

Morschhäuser J. Regulation of multidrug resistance in pathogenic fungi. Fungal Genetics and Biology. 2010;47(2):94–106. PubMed

Duval AR, Carvalho PH, Soares MC, et al. 7-Chloroquinolin-4-yl arylhydrazone derivatives: synthesis and antifungal activity. TheScientificWorldJOURNAL. 2011;11:1489–1495. PubMed PMC

Vinsova J, Imramovsky A, Buchta V, et al. Salicylanilide acetates: synthesis and antibacterial evaluation. Molecules. 2007;12(1):1–12. PubMed PMC

Imramovský A, Vinšová J, Férriz JM, Buchta V, Jampílek J. Salicylanilide esters of N-protected amino acids as novel antimicrobial agents. Bioorganic and Medicinal Chemistry Letters. 2009;19(2):348–351. PubMed

Krátký M, Vinšová J, Buchta V, Horvati K, Bösze S, Stolaříková J. New amino acid esters of salicylanilides active against MDR-TB and other microbes. European Journal of Medicinal Chemistry. 2010;45(12):6106–6113. PubMed

Cheng TJR, Wu YT, Yang ST, et al. High-throughput identification of antibacterials against methicillin-resistant Staphylococcus aureus (MRSA) and the transglycosylase. Bioorganic and Medicinal Chemistry. 2010;18(24):8512–8529. PubMed

Melliou E, Chinou I. Chemical analysis and antimicrobial activity of Greek propolis. Planta Medica. 2004;70(6):515–519. PubMed

Kong WK, Zhao YL, Shan LM, Xiao XH, Guo WY. Thermochemical studies on the quantity—antibacterial effect relationship of four organic acids from Radix isatidis on Escherichia coli growth. Biological and Pharmaceutical Bulletin. 2008;31(7):1301–1305. PubMed

Alvesalo J, Vuorela H, Tammela P, Leinonen M, Saikku P, Vuorela P. Inhibitory effect of dietary phenolic compounds on Chlamydia pneumoniae in cell cultures. Biochemical Pharmacology. 2006;71(6):735–741. PubMed

Kubo I, Xiao P, Nihei KI, Fujita KI, Yamagiwa Y, Kamikawa T. Molecular design of antifungal agents. Journal of Agricultural and Food Chemistry. 2002;50(14):3992–3998. PubMed

Cho JY, Moon JH, Seong KY, Park KH. Antimicrobial activity of 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid isolated and identified from rice hull. Bioscience, Biotechnology, and Biochemistry. 1998;62(11):2273–2276. PubMed

Nishina A, Kajishima F, Matsunaga M, Tezuka H, Inatomi H, Osawa T. Antimicrobial substance, 3’,4’-dihydroxyacetophenone, in coffee residue. Bioscience, Biotechnology, and Biochemistry. 1994;58(2):293–296.

Innocenti A, Hall RA, Schlicker C, Muhlschlegel FA, Supuran CT. Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates. Bioorganic and Medicinal Chemistry. 2009;17(7):2654–2657. PubMed

Brul S, Coote P. Preservative agents in foods: mode of action and microbial resistance mechanisms. International Journal of Food Microbiology. 1999;50(1-2):1–17. PubMed

Clinical and Laboratory Standards Institute (CLSI) Methods for dilution antimicrobial susceptibility test for bacteria that growth aerobically. Approved Standard—7th edition, 2011, http://www.clsi.org/source/orders/free/m11a7.pdf.

Clinical and Laboratory Standards Institute (CLSI) Reference method for brothdilution antifungal susceptibility testing of filamentous fungi. Approved Standard—2nd edition, 2011, http://www.clsi.org/source/orders/free/M38-a2.pdf.

Clinical and Laboratory Standards Institute (CLSI) Reference method for broth dilution antifungal susceptibility testing of yeasts. Approved Standard—3rd edition, 2011, http://www.clsi.org/source/orders/free/M27-A3.pdf.

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