Mycobacterium avium subsp. avium and Mycobacterium neoaurum detection in an immunocompromised patient
Jazyk angličtina Země Anglie, Velká Británie Médium print-electronic
Typ dokumentu kazuistiky, časopisecké články, práce podpořená grantem
PubMed
23842543
PubMed Central
PMC9151095
DOI
10.1017/s0950268813001660
PII: S0950268813001660
Knihovny.cz E-zdroje
- MeSH
- antituberkulotika terapeutické užití MeSH
- antitumorózní látky terapeutické užití MeSH
- atypické mykobakteriální infekce * MeSH
- ciprofloxacin terapeutické užití MeSH
- hostitel s imunodeficiencí * MeSH
- lidé MeSH
- mikrobiologie životního prostředí MeSH
- mladiství MeSH
- Mycobacterium avium izolace a purifikace MeSH
- nehodgkinský lymfom farmakoterapie MeSH
- netuberkulózní mykobakterie izolace a purifikace MeSH
- sputum mikrobiologie MeSH
- střevní sliznice mikrobiologie MeSH
- tuberkulóza * MeSH
- Check Tag
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- práce podpořená grantem MeSH
- Názvy látek
- antituberkulotika MeSH
- antitumorózní látky MeSH
- ciprofloxacin MeSH
Non-tuberculous mycobacteria are increasingly described as infectious agents in immunocompromised patients. A 17-year-old male patient suffering from secondary non-Hodgkin's lymphoma and treated with chemotherapeutic agents was admitted to hospital due to pleuropneumonia. Mycobacterium neoaurum was cultured repeatedly from his sputum and, Mycobacterium avium subsp. avium (M. a. avium) was detected by IS901 qPCR from detached fragments of his intestinal mucosa. We attempted to determine the possible sources of infection by analysing environmental samples from the closed oncology unit and conventional unit in the hospital, and from the patient's home residence and places which he frequented. The environment of the patient harboured mycobacteria (41 isolates in total); however, M. neoaurum was not recovered. M. a. avium was detected by qPCR in the environmental samples from a small flock of hens kept by his neighbour. Although it was not confirmed by DNA fingerprinting methods, the M. a. avium infection could have been acquired through the eating of incompletely cooked eggs.
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