Fluorescein analogue xanthene-9-carboxylic acid: a transition-metal-free CO releasing molecule activated by green light
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
23957602
DOI
10.1021/ol4021089
Knihovny.cz E-resources
- MeSH
- Fluorescein chemistry MeSH
- Carboxyhemoglobin chemistry MeSH
- Molecular Structure MeSH
- Carbon Monoxide chemistry MeSH
- Light MeSH
- Water chemistry MeSH
- Xanthenes chemistry MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Fluorescein MeSH
- Carboxyhemoglobin MeSH
- Carbon Monoxide MeSH
- Water MeSH
- xanthene-9-carboxylic acid MeSH Browser
- Xanthenes MeSH
6-Hydroxy-3-oxo-3H-xanthene-9-carboxylic acid is introduced as the first transition-metal-free carbon monoxide releasing molecule activated by visible light (photoCORM). This water-soluble fluorescein analogue releases carbon monoxide in both water and methanol upon irradiation at 500 nm. When selectively irradiated in the presence of hemoglobin (Hb) under physiological conditions, released CO is quantitatively trapped to form carboxyhemoglobin (COHb). The reaction progress can be accurately monitored by characteristic absorption and emission properties of the reactants and products.
References provided by Crossref.org
Visible-Light-Activated Carbon Monoxide Release from Porphyrin-Flavonol Hybrids
The complex photochemistry of coumarin-3-carboxylic acid in acetonitrile and methanol
Antiproliferative and Cytotoxic Activities of Fluorescein-A Diagnostic Angiography Dye
Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials
Cyanine-Flavonol Hybrids for Near-Infrared Light-Activated Delivery of Carbon Monoxide
Light-Activated Carbon Monoxide Prodrugs Based on Bipyridyl Dicarbonyl Ruthenium(II) Complexes
