Host response to Borrelia afzelii in BALB/c mice tested by immunoblotting
Jazyk angličtina Země Polsko Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
24364462
PII: 1081399
Knihovny.cz E-zdroje
- MeSH
- antigeny bakteriální imunologie MeSH
- Borrelia burgdorferi komplex klasifikace MeSH
- imunoblotting * MeSH
- lymeská nemoc imunologie mikrobiologie MeSH
- myši inbrední BALB C MeSH
- myši MeSH
- protilátky bakteriální krev MeSH
- specificita protilátek MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- myši MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- antigeny bakteriální MeSH
- protilátky bakteriální MeSH
The aim was to find if there is variability in the production of specific antibodies by BALB/c mice to certain antigens of three individual Borrelia afzelii (dead cell suspension) strains originally isolated from different sources. Analysis of the borrelian proteins immunogenicity was performed and determined to particular strains by immunoblotting. Some differences in production of specific IgM and IgG antibodies in each individual group of tested mice were found. The antigenic influence of OspA and OspC proteins appeared to be the most important for the induction of protective immune reaction. OspC was produced both in early and late infection of all individuals and OspA induced production of IgG antibodies in all groups of immunized mice.
Wild Small Mammals and Ticks in Zoos-Reservoir of Agents with Zoonotic Potential?
