Why do we have Purkinje fibers deep in our heart?
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
24564668
DOI
10.33549/physiolres.932686
PII: 932686
Knihovny.cz E-resources
- MeSH
- Action Potentials physiology MeSH
- Models, Anatomic * MeSH
- Biological Clocks physiology MeSH
- Humans MeSH
- Models, Cardiovascular * MeSH
- Purkinje Fibers cytology physiology MeSH
- Excitation Contraction Coupling physiology MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Purkinje fibers were the first discovered component of the cardiac conduction system. Originally described in sheep in 1839 as pale subendocardial cells, they were found to be present, although with different morphology, in all mammalian and avian hearts. Here we review differences in their appearance and extent in different species, summarize the current state of knowledge of their function, and provide an update on markers for these cells. Special emphasis is given to popular model species and human anatomy.
References provided by Crossref.org
Jan Evangelista Purkinje: A Passion for Discovery
Trabecular Architecture Determines Impulse Propagation Through the Early Embryonic Mouse Heart