Plicní mukormykóza vyvolaná Rhizopus microsporus
[Pulmonary mucormycosis caused by Rhizopus microsporus]
Language Czech Country Czech Republic Media print
Document type Case Reports, Journal Article
PubMed
24623054
- MeSH
- Leukemia, Myeloid, Acute complications MeSH
- Amphotericin B pharmacology therapeutic use MeSH
- Antifungal Agents pharmacology therapeutic use MeSH
- Humans MeSH
- Mucormycosis * diagnosis drug therapy microbiology surgery MeSH
- Lung Diseases, Fungal * diagnosis drug therapy microbiology surgery MeSH
- Rhizopus * drug effects isolation & purification MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Names of Substances
- Amphotericin B MeSH
- Antifungal Agents MeSH
We report a case of mycotic pneumonia in a patient with acute myeloblastic leukemia. Rhizopus microsporus was identified as an agent of mucormycosis and proven by microscopy and culture. The determination of the isolate was supported by molecular methods. Combined treatment with surgery (right-sided pneumonectomy) and systemic amphotericin B and posaconazole antifungal therapy was chosen. In this case, amphotericin B Neo-Sensitabs tablets gave false "resistant" results on Mueller-Hinton agar when using the disk diffusion test. There was a good correlation between the Etest (16 h) and the Sensititre YeastOne microplate (24 h) for amphotericin B.
