Supercritical fluid chromatography as a tool for enantioselective separation; a review
Language English Country Netherlands Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
24703210
DOI
10.1016/j.aca.2014.02.036
PII: S0003-2670(14)00249-9
Knihovny.cz E-resources
- Keywords
- Chiral stationary phase, Enantiomers, Enantioselective separation, Review, Supercritical fluid chromatography,
- MeSH
- Equipment Design MeSH
- Glycopeptides chemistry MeSH
- Molecular Imprinting MeSH
- Polymers chemistry MeSH
- Polysaccharides chemistry MeSH
- Stereoisomerism MeSH
- Chromatography, Supercritical Fluid instrumentation methods MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Glycopeptides MeSH
- Polymers MeSH
- Polysaccharides MeSH
Supercritical fluid chromatography (SFC) has become popular in the field of enantioselective separations. Many works have been reported during the last years. This review covers the period from 2000 till August 2013. The article is divided into three main chapters. The first one comprises a basic introduction to SFC. The authors provide a brief explanation of general principles and possibilities of this method. The advantages and drawbacks are also listed. Next part deals with chiral separation systems available in SFC, namely with the commonly used chiral stationary phases. Properties and interaction possibilities of the chiral separation systems are described. Recent theoretical papers are emphasized in this chapter. The last part of the paper gives an overview of applications of enantioselective SFC in analytical chemistry, in both analytical and preparative scales. Separation systems and conditions are summed up in tables so that they provide a helpful tool for analysts who search for a particular method of analysis.
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