(Self-) infections with parasites: re-interpretations for the present
Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
PubMed
25033775
DOI
10.1016/j.pt.2014.06.005
PII: S1471-4922(14)00108-1
Knihovny.cz E-zdroje
- Klíčová slova
- autoimmune diseases, helminth therapy, helminths, protists, self-infection, volunteers,
- MeSH
- autoimunitní nemoci parazitologie terapie MeSH
- cizopasní červi imunologie MeSH
- Eukaryota imunologie MeSH
- imunitní systém - jevy MeSH
- interakce hostitele a parazita MeSH
- lékařská etika MeSH
- lidé MeSH
- parazitární nemoci imunologie přenos MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
Previously, scientists sometimes resorted to infecting themselves or colleagues with parasites, usually to assess the pathogenicity and obtain insight into the life cycles of the parasites, host specificity, and epidemiology. However, with recent research addressing the possible beneficial impact of intestinal helminths on a range of immune-mediated diseases in humans, these studies offer valuable information, although many are now considered unethical owing to a lack of experimental oversight and informed consent. Here, we critically review cases in which humans were deliberately infected with parasites. Moreover, we summarize the contribution of (self-) infections and propose protist and helminth candidates, chosen on the basis of several criteria, to test as possible therapy for selected human diseases.
Citace poskytuje Crossref.org
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