Curcuma and Scutellaria plant extracts protect chickens against inflammation and Salmonella Enteritidis infection
Language English Country Great Britain, England Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
26188032
DOI
10.3382/ps/pev190
PII: S0032-5791(19)32239-4
Knihovny.cz E-resources
- Keywords
- Curcuma, Salmonella, Scutellaria, chicken, feed, flavonoid, inflammation,
- MeSH
- Anti-Bacterial Agents administration & dosage pharmacology MeSH
- Anti-Inflammatory Agents administration & dosage pharmacology MeSH
- Curcuma chemistry MeSH
- Diet veterinary MeSH
- Animal Feed analysis MeSH
- Chickens * MeSH
- Microbiota drug effects MeSH
- Poultry Diseases drug therapy immunology microbiology MeSH
- Dietary Supplements analysis MeSH
- RNA, Ribosomal, 16S genetics metabolism MeSH
- Plant Extracts administration & dosage pharmacology MeSH
- Salmonella enteritidis drug effects physiology MeSH
- Salmonella Infections, Animal drug therapy microbiology MeSH
- Scutellaria chemistry MeSH
- Inflammation drug therapy veterinary MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Anti-Inflammatory Agents MeSH
- RNA, Ribosomal, 16S MeSH
- Plant Extracts MeSH
After a ban on the use of antibiotics as growth promoters in farm animals in the European Union in 2006, an interest in alternative products with antibacterial or anti-inflammatory properties has increased. In this study, we therefore tested the effects of extracts from Curcuma longa and Scutellaria baicalensis used as feed additives against cecal inflammation induced by heat stress or Salmonella Enteritidis (S. Enteritidis) infection in chickens. Curcuma extract alone was not enough to decrease gut inflammation induced by heat stress. However, a mixture of Curcuma and Scutellaria extracts used as feed additives decreased gut inflammation induced by heat or S. Enteritidis, decreased S. Enteritidis counts in the cecum but was of no negative effect on BW or humoral immune response. Using next-generation sequencing of 16S rRNA we found out that supplementation of feed with the 2 plant extracts had no effect on microbiota diversity. However, if the plant extract supplementation was provided to the chickens infected with S. Enteritidis, Faecalibacterium, and Lactobacillus, both bacterial genera with known positive effects on gut health were positively selected. The supplementation of chicken feed with extracts from Curcuma and Scutelleria thus may be used in poultry production to effectively decrease gut inflammation and increase chicken performance.
CCPA Group Z A du Bois de Teillay 35150 Janze France
Veterinary Research Institute Hudcova 70 621 00 Brno Czech Republic
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