Disseminated fusariosis by Fusarium proliferatum in a patient with aplastic anaemia receiving primary posaconazole prophylaxis - case report and review of the literature
Language English Country Germany Media print-electronic
Document type Case Reports, Journal Article, Research Support, Non-U.S. Gov't
PubMed
26661324
DOI
10.1111/myc.12421
Knihovny.cz E-resources
- Keywords
- Fusarium proliferatum, PCR diagnostics, fusariosis, real-time PCR,
- MeSH
- Antifungal Agents pharmacology therapeutic use MeSH
- Anemia, Aplastic complications MeSH
- Aspergillus flavus drug effects isolation & purification MeSH
- Aspergillosis complications microbiology MeSH
- Fatal Outcome MeSH
- Fusariosis complications diagnosis drug therapy microbiology MeSH
- Fusarium drug effects isolation & purification MeSH
- Immunocompromised Host * MeSH
- Coinfection MeSH
- Humans MeSH
- Young Adult MeSH
- Opportunistic Infections diagnosis drug therapy microbiology MeSH
- Triazoles therapeutic use MeSH
- Check Tag
- Humans MeSH
- Young Adult MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Antifungal Agents MeSH
- posaconazole MeSH Browser
- Triazoles MeSH
Disseminated fusariosis is a life-threatening, invasive, opportunistic infection in immunocompromised patients, especially those with haematological malignancies. The prognosis is poor because these fungi are resistant to many of the available antifungal agents. We present a case of disseminated fusariosis caused by Fusarium proliferatum in a patient with severe aplastic anaemia complicated by a secondary infection of Aspergillus flavus, with a fatal outcome. We also review the documented Fusarium infections in immunocompromised hosts.
CEITEC Central European Institute of Technology Masaryk University Brno Czech Republic
Department of Clinical Microbiology University Hospital Brno Brno Czech Republic
Department of Internal Medicine Hematology and Oncology University Hospital Brno Brno Czech Republic
Department of Pathology University Hospital Brno Brno Czech Republic
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