This work discusses several selected topics of plant genetics and breeding in relation to the 150th anniversary of the seminal work of Gregor Johann Mendel. In 2015, we celebrated the 150th anniversary of the presentation of the seminal work of Gregor Johann Mendel. While Darwin's theory of evolution was based on differential survival and differential reproductive success, Mendel's theory of heredity relies on equality and stability throughout all stages of the life cycle. Darwin's concepts were continuous variation and "soft" heredity; Mendel espoused discontinuous variation and "hard" heredity. Thus, the combination of Mendelian genetics with Darwin's theory of natural selection was the process that resulted in the modern synthesis of evolutionary biology. Although biology, genetics, and genomics have been revolutionized in recent years, modern genetics will forever rely on simple principles founded on pea breeding using seven single gene characters. Purposeful use of mutants to study gene function is one of the essential tools of modern genetics. Today, over 100 plant species genomes have been sequenced. Mapping populations and their use in segregation of molecular markers and marker-trait association to map and isolate genes, were developed on the basis of Mendel's work. Genome-wide or genomic selection is a recent approach for the development of improved breeding lines. The analysis of complex traits has been enhanced by high-throughput phenotyping and developments in statistical and modeling methods for the analysis of phenotypic data. Introgression of novel alleles from landraces and wild relatives widens genetic diversity and improves traits; transgenic methodologies allow for the introduction of novel genes from diverse sources, and gene editing approaches offer possibilities to manipulate gene in a precise manner.

Crop Development Centre University of Saskatchewan Saskatoon SK Canada

Department of Botany Faculty of Sciences Palacký University in Olomouc Slechtitelu 27 Olomouc Czech Republic

Department of Plant Developmental Genetics Institute of Biophysics Czech Academy of Sciences Brno Czech Republic

International Crops Research Institute for the Semi Arid Tropics Patancheru Hyderabad India

John Innes Centre Norwich Research Park Norwich UK

USDA ARS Washington State University Pullman USA

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New Phytol. 2013 Oct;200(1):276-83 PubMed

Nature. 1988 Oct 20;335(6192):721-6 PubMed

Heredity (Edinb). 2014 Jan;112(1):48-60 PubMed

Annu Rev Plant Biol. 2010;61:349-72 PubMed

Mol Biol Evol. 2013 May;30(5):1015-31 PubMed

Am J Hum Genet. 1999 Jul;65(1):220-8 PubMed

Nature. 2006 Oct 5;443(7111):521-4 PubMed

PLoS Genet. 2015 Feb 17;11(2):e1004982 PubMed

PLoS Biol. 2005 Jun;3(6):e181 PubMed

Nature. 2000 Dec 14;408(6814):796-815 PubMed

Nat Biotechnol. 2012 May 07;30(5):390-2 PubMed

Science. 1903 Sep 25;18(456):396-406 PubMed

Q Rev Biol. 1995 Sep;70(3):297-320 PubMed

Am J Hum Genet. 1980 May;32(3):314-31 PubMed

Curr Biol. 1995 Jul 1;5(7):737-9 PubMed

Genetics. 2000 Jan;154(1):7-11 PubMed

J Mol Biol. 1975 May 25;94(3):441-8 PubMed

Cold Spring Harb Symp Quant Biol. 1986;51 Pt 1:263-73 PubMed

Trends Plant Sci. 2011 Nov;16(11):590-6 PubMed

Proc Natl Acad Sci U S A. 1950 Nov;36(11):643-54 PubMed

Cell. 1990 Jan 12;60(1):115-22 PubMed

Heredity (Edinb). 2014 Jan;112(1):30-8 PubMed

Nat Biotechnol. 2012 Jan 22;30(2):174-8 PubMed

Genetics. 2006 Jun;173(2):1047-56 PubMed

Ann Bot. 2009 Jan;103(2):151-60 PubMed

Theor Appl Genet. 2007 Oct;115(6):767-76 PubMed

Science. 2010 Feb 12;327(5967):818-22 PubMed

New Phytol. 2007;175(4):756-63 PubMed

Am J Bot. 2001 May;88(5):737-52 PubMed

Nature. 2009 May 21;459(7245):442-5 PubMed

Plant J. 2011 Aug;67(4):715-25 PubMed

Isis. 1951 Jun;42(128):97-104 PubMed

Rice (N Y). 2015 Dec;8(1):51 PubMed

Nat Genet. 2001 Jul;28(3):286-9 PubMed

Genetics. 1989 Jan;121(1):185-99 PubMed

Nat Rev Genet. 2002 Nov;3(11):883-9 PubMed

Trends Biotechnol. 2009 Sep;27(9):522-30 PubMed

PLoS One. 2014 Dec 08;9(12):e113583 PubMed

Genetics. 1916 Mar;1(2):164-76 PubMed

Plant Biol (Stuttg). 2006 Nov;8(6):770-7 PubMed

Nature. 1980 Apr 17;284(5757):604-7 PubMed

Plant Sci. 2016 Jan;242:278-287 PubMed

Nat Rev Genet. 2008 May;9(5):397-405 PubMed

Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):1971-4 PubMed

Trends Biotechnol. 2013 Jul;31(7):397-405 PubMed

Plant Sci. 2016 Jan;242:330-341 PubMed

Bioessays. 2006 Sep;28(9):913-22 PubMed

Genetics. 2002 Dec;162(4):1945-59 PubMed

Genetics. 2006 Jan;172(1):1-6 PubMed

Science. 2000 Jul 7;289(5476):85-8 PubMed

Theor Appl Genet. 2016 Dec;129(12):2241-2252 PubMed

Plant Physiol. 2012 Oct;160(2):591-600 PubMed

Methods Cell Sci. 2001;23(1-3):57-69 PubMed

Curr Opin Plant Biol. 2015 Apr;24:71-81 PubMed

Plant J. 2010 Mar;61(6):909-21 PubMed

Trends Genet. 2001 Jan;17(1):23-8 PubMed

PLoS One. 2010 Oct 11;5(10):e13230 PubMed

Curr Opin Plant Biol. 2005 Apr;8(2):148-54 PubMed

Plant J. 2001 Dec;28(6):689-97 PubMed

Plant Cell Physiol. 2015 Mar;56(3):389-400 PubMed

Genetics. 2011 Sep;189(1):3-10 PubMed

Nature. 2003 Mar 27;422(6930):433-8 PubMed

Science. 2015 Oct 9;350(6257):159-60 PubMed

Science. 2004 Sep 17;305(5691):1786-9 PubMed

Arch Hist Exact Sci. 1980;22(4):323-71 PubMed

Science. 1921 Sep 9;54(1393):223 PubMed

Nat Methods. 2009 Aug;6(8):550-1 PubMed

Plant Sci. 2016 Jan;242:203-213 PubMed

Trends Ecol Evol. 2009 Oct;24(10):572-82 PubMed

Science. 1996 Sep 13;273(5281):1516-7 PubMed

Alzheimers Dement. 2016 Jan;12(1):1 PubMed

Curr Opin Genet Dev. 2007 Dec;17(6):545-52 PubMed

Theor Appl Genet. 2015 Jul;128(7):1243-59 PubMed

Genetics. 1950 Sep;35(5 2):1-29 PubMed

Genetics. 1923 Nov;8(6):552-60 PubMed

Science. 2004 Mar 12;303(5664):1626-32 PubMed

Theor Appl Genet. 2013 Jun;126(6):1639-47 PubMed

Plant Cell. 1997 Sep;9(9):1509-1514 PubMed

Proc Natl Acad Sci U S A. 1977 Feb;74(2):560-4 PubMed

Nature. 2008 Nov 6;456(7218):53-9 PubMed

Nucleus. 2010 May-Jun;1(3):284-97 PubMed

Genetics. 2007 Mar;175(3):975-9 PubMed

Theor Appl Genet. 1983 Nov;67(1):35-43 PubMed

Genetics. 2001 Apr;157(4):1819-29 PubMed

Theor Appl Genet. 2014 Feb;127(2):445-62 PubMed

Plant Physiol. 2001 Jan;125(1):15-9 PubMed

Nat Rev Genet. 2001 Dec;2(12):983-9 PubMed

Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463-7 PubMed

Mol Cell Biol. 1992 Sep;12(9):3910-8 PubMed

Science. 1966 Jun 10;152(3728):1463-9 PubMed

Genome Res. 2011 Dec;21(12):2038-48 PubMed

Theor Appl Genet. 1975 Jan;46(7):319-30 PubMed

Am J Hum Genet. 1984 May;36(3):495-8 PubMed

Mol Biol Evol. 2004 Sep;21(9):1613-9 PubMed

New Phytol. 2010 Apr;186(1):148-60 PubMed

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2730-5 PubMed

Plant Biotechnol J. 2016 May;14(5):1183-94 PubMed

Science. 2012 Aug 17;337(6096):816-21 PubMed

Trends Genet. 1997 Apr;13(4):141-5 PubMed

Nature. 2009 May 21;459(7245):437-41 PubMed

Nat Rev Genet. 2004 Jun;5(6):435-45 PubMed

Theor Appl Genet. 2016 Dec;129(12):2323-2332 PubMed

Trends Genet. 2014 Sep;30(9):418-26 PubMed

Genetics. 2012 Aug;191(4):1381-6 PubMed

Nat Biotechnol. 2013 Sep;31(9):822-6 PubMed

Genetics. 2000 Jun;155(2):945-59 PubMed

Proc Natl Acad Sci U S A. 1950 Jun;36(6):344-55 PubMed

PLoS One. 2013 Jul 10;8(7):e68529 PubMed

Mol Biol Evol. 2003 Jun;20(6):880-92 PubMed

Mol Genet Genomic Med. 2015 Jan;3(1):1-7 PubMed

Genetics. 1992 Jun;131(2):245-53 PubMed

Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9903-8 PubMed

Nat Biotechnol. 2013 Aug;31(8):688-91 PubMed

Ann Bot. 2008 Apr;101(6):791-804 PubMed

Science. 2013 Feb 15;339(6121):819-23 PubMed

Genetics. 1988 Dec;120(4):1095-103 PubMed

Nat Rev Genet. 2007 Dec;8(12):973-82 PubMed

Nat Biotechnol. 2013 Aug;31(8):686-8 PubMed

Theor Appl Genet. 2014 Aug;127(8):1771-81 PubMed

Proc Natl Acad Sci U S A. 1931 Aug;17(8):492-7 PubMed

Anal Biochem. 1996 Nov 1;242(1):84-9 PubMed

Ann Bot. 2005 Jan;95(1):45-90 PubMed

Nature. 1980 Apr 17;284(5757):601-3 PubMed

Brief Funct Genomics. 2012 Jan;11(1):3-11 PubMed

Genetics. 1987 May;116(1):113-25 PubMed

Am J Med Genet. 1991 Jul 1;40(1):1-25; discussion 26 PubMed

Bioessays. 2009 Jul;31(7):703-14 PubMed

Nature. 2006 Aug 10;442(7103):705-8 PubMed

Legume Genetics and Biology: From Mendel's Pea to Legume Genomics