Drug carriers with star polymer structures
Language English Country Czech Republic Media print
Document type Journal Article, Review
PubMed
30379551
DOI
10.33549/physiolres.933978
PII: 933978
Knihovny.cz E-resources
- MeSH
- Humans MeSH
- Methacrylates administration & dosage chemistry metabolism MeSH
- Drug Carriers administration & dosage chemistry metabolism MeSH
- Polyethylene Glycols administration & dosage metabolism MeSH
- Polymers administration & dosage chemistry metabolism MeSH
- Tissue Distribution drug effects physiology MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- hydroxypropyl methacrylate MeSH Browser
- Methacrylates MeSH
- Drug Carriers MeSH
- Polyethylene Glycols MeSH
- Polymers MeSH
In this review we summarize several synthetic approaches to the advanced synthesis of star-like polymer-based drug carriers. Moreover, their application as nanomedicines for therapy or the diagnosis of neoplastic diseases and their biodistribution are reviewed in detail. From a broad spectrum of star-like systems, we focus only on fully water-soluble systems, mainly based on poly(ethylene glycol) or N-(2-hydroxypropyl)methacrylamide polymer and copolymer arms and polyamidoamine dendrimers serving as the core of the star-like systems.
References provided by Crossref.org
Evaluation of linear versus star-like polymer anti-cancer nanomedicines in mouse models
HPMA Copolymer-Based Nanomedicines in Controlled Drug Delivery