Recent developments and applications of capillary and microchip electrophoresis in proteomics and peptidomics (2015-mid 2018)
Jazyk angličtina Země Německo Médium print-electronic
Typ dokumentu časopisecké články, přehledy
Grantová podpora
17-10832S
Czech Science Foundation
18-02597S
Czech Science Foundation
RVO 61388963
Czech Academy of Sciences
PubMed
30457207
DOI
10.1002/jssc.201801090
Knihovny.cz E-zdroje
- Klíčová slova
- capillary electrophoresis, mass spectrometry, microchip electrophoresis, peptidomics, proteomics,
- MeSH
- elektroforéza kapilární MeSH
- lidé MeSH
- peptidomimetika analýza MeSH
- peptidy analýza MeSH
- proteiny analýza MeSH
- proteomika * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- Názvy látek
- peptidomimetika MeSH
- peptidy MeSH
- proteiny MeSH
This review summarizes recent developments and applications of capillary and microchip electroseparation methods in proteomic and peptidomic analyses since the year 2015 to ca. mid 2018. Sample preparation procedures for the removal of interfering components or for pre-fractionation and preconcentration of proteins and peptides of interest are discussed. The innovations in coupling of capillary or microchip electroseparation methods with different modes of mass spectrometry detection are covered. In addition, significant recent applications of capillary electromigration methods in both bottom-up and top-down proteomics as well as in determinations of post-translational modifications of proteins are presented. Moreover, several examples of the utilization of capillary electromigration methods coupled with mass spectrometry detection for clinical proteomics and peptidomics are described.
Citace poskytuje Crossref.org
Peptidomics and Capillary Electrophoresis
Microfluidics for Peptidomics, Proteomics, and Cell Analysis
