Validation and inter-laboratory study of selective hydride generation for fast screening of inorganic arsenic in seafood
Language English Country Netherlands Media print-electronic
Document type Journal Article
PubMed
30612652
DOI
10.1016/j.aca.2018.11.036
PII: S0003-2670(18)31392-8
Knihovny.cz E-resources
- Keywords
- Certified reference materials, Inductively coupled plasma mass spectrometry, Inorganic arsenic, Interlaboratory comparison, Selective hydride generation, Speciation analysis,
- MeSH
- Arsenic analysis MeSH
- Decapoda chemistry MeSH
- Decapodiformes chemistry MeSH
- Mass Spectrometry methods MeSH
- Food Contamination analysis MeSH
- Hydrochloric Acid chemistry MeSH
- Limit of Detection MeSH
- Shellfish analysis MeSH
- Bivalvia chemistry MeSH
- Seaweed chemistry MeSH
- Perchlorates chemistry MeSH
- Hydrogen Peroxide chemistry MeSH
- Fish Proteins, Dietary analysis MeSH
- Dogfish MeSH
- Hydrogen chemistry MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Arsenic MeSH
- Hydrochloric Acid MeSH
- Perchlorates MeSH
- Perchloric Acid MeSH Browser
- Hydrogen Peroxide MeSH
- Fish Proteins, Dietary MeSH
- Hydrogen MeSH
It is advisable to monitor and regulate inorganic arsenic (iAs) in food and feedstuff. This work describes an update and validation of a method of selective hydride generation (HG) with inductively coupled plasma mass spectrometry (ICP-MS) for high-throughput screening of iAs content in seafood samples after microwave-assisted extraction with diluted nitric acid and hydrogen peroxide. High concentration of HCl (8 M) for HG along with hydrogen peroxide in samples of a same concentration as used for extraction leads to a selective conversion of iAs to volatile arsine that is released and transported to the detector. A minor contribution from methylarsonate (≈20% to iAs) was found, while HG from dimethylarsinate, trimethylarsine oxide is substantially suppressed (less than 1% to iAs). Methodology was applied to Certified Reference Materials (CRMs) TORT-3, DORM-3, DORM-4, DOLT-4, DOLT-5, PRON-1, SQID-1 and ERM-CE278k, in some of them iAs has been determined for the first time, and to various seaweed samples from a local store. The results were always compared with a reference method and selectivity of iAs determination was evaluated. An inter-laboratory reproducibility was tested by comparative analyses of six fish and four seaweed samples in three European laboratories, with good agreement of the results. The method of HG-ICP-MS is sensitive (limit of detection 2 μg kg-1 iAs), well suited for screening of large number of samples and selective at iAs concentration levels at which maximum limits are expected to be set into EU legislation for marine samples.
Matís Research and Innovation Vinlandsleid 12 113 Reykjavik Iceland
National Research Council of Canada 1200 Montreal Road Ottawa Ontario K1A 0R6 Canada
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