JavaScript is NOT enabled !

Please enable JavaScript.

Article

PubMed

This record comes from PubMed

Oral anticoagulation in patients with non-valvular atrial fibrillation and a CHA2DS2-VASc score of 1: a current opinion of the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy and European Society of Cardiology Council on Stroke

Sulzgruber, Patrick
Author Sulzgruber, Patrick Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria
Wassmann, Sven
Author Wassmann, Sven Cardiology Pasing, Institutstraße 14, 81241 Munich, Germany University of the Saarland, Kirrberger Straße 100, 66424 Homburg, Saar, Germany
Semb, Anne Grete
Author Semb, Anne Grete Department of Rheumatology, Preventive Cardio-Rheuma Clinic, Diakonhjemmet Hospital, Diakonveien 12, 0370 Oslo, Norway
Doehner, Wolfram
Author Doehner, Wolfram Department of Cardiology (Virchow Klinikum), German Centre for Cardiovascular Research (DZHK), Oudenarder Straße 16, 13316 Berlin, Germany BIH Center for Regenerative Therapies (BCRT), Charité Universitaetsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany
Widimsky, Petr
Author Widimsky, Petr Cardiocenter, Third Faculty of Medicine, Charles University, Opletalova 38, 110 00 Staré Město, Prague, Czech Republic
Gremmel, Thomas
Author Gremmel, Thomas Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria Department of Internal Medicine, Cardiology and Nephrology, Landesklinikum Wiener Neustadt, Corvinusring 3-5, 2700 Wiener Neustadt, Austria
Kaski, Juan Carlos
Author Kaski, Juan Carlos Molecular and Clinical Sciences Research Institute, St George's, University of London, Cranmer Terrace, Tooting, London SW17 0RE, UK
Savarese, Gianluigi
Author Savarese, Gianluigi Cardiology Division, Department of Medicine, Karolinska Institute, Karolinska University Hospital, Eugeniavägen 3, 171 76 Solna, Stockholm, Sweden
Rosano, Giuseppe M C
Author Rosano, Giuseppe M C IRCCS San Raffaele Roma, Via della Pisana, 235, 00163 Roma, Italy St George's Hospitals NHS Trust, University of London, Cranmer Terrace, Tooting, London SW17 0RE, UK
Borghi, Claudio
Author Borghi, Claudio Atherosclerosis Research Unit, Medical and Surgical Sciences Department, Sant'Orsola-Malpighi Hospital, University of Bologna, Via Zamboni, 33, 40126 Comune di Bologna BO, Italy
Kjeldsen, Keld
Author Kjeldsen, Keld Department of Cardiology, Copenhagen University Hospital (Hvidovre-Amager), Blegdamsvej 9, 2100 Copenhagen, Denmark Department of Health Science and Technology, The Faculty of Medicine, Aalborg University, Fredrik Bajers Vej 5, 9100 Aalborg, Denmark
Torp-Pedersen, Christian
Author Torp-Pedersen, Christian Department of Health Sciences and Technology, Aalborg University, Fredrik Bajers Vej 5, 9100 Aalborg, Denmark Department of Cardiology, Aalborg University Hospital, Fredrik Bajers Vej 5, 9100 Aalborg, Denmark
Schmidt, Thomas Andersen
Author Schmidt, Thomas Andersen Emergency Department, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen, Denmark
Lewis, Basil S
Author Lewis, Basil S Lady Davis Carmel Medical Center, Mikhal St 7, 3436212 Haifa, Israel Technion-Israel Institute of Technology, Ruth and Bruce Rappaport School of Medicine, Efron St 1, 3436212 Haifa, Israel
Drexel, Heinz
Author Drexel, Heinz VIVIT Research, Landeskrankenhaus Feldkirch, Carinagasse 47, 6800 Feldkirch, Austria Private University of the Principality of Liechtenstein, Dorfstrasse 24. FL-9495 Triesen, Principality of Liechtenstein
Tamargo, Juan
Author Tamargo, Juan Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense, Avda. de Séneca, 2 Ciudad Universitaria, 28040 Madrid, Spain
Atar, Dan
Author Atar, Dan Department of Cardiology, Oslo University Hospital and Institute of Clinical Medicine, Oslo University, Klaus Torgírds vei 3, 0372 Oslo, Norway
Agewall, Stefan
Author Agewall, Stefan Department of Cardiology, Oslo University Hospital and Institute of Clinical Medicine, Oslo University, Klaus Torgírds vei 3, 0372 Oslo, Norway
Niessner, Alexander
Author Niessner, Alexander Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria

European heart journal. Cardiovascular pharmacotherapy. 2019 Jul 01 ; 5 (3) : 171-180.

Eur Heart J Cardiovasc Pharmacother
ISSN 2055-6845
Source

Language English Country Great Britain, England Media print

Document type Journal Article, Practice Guideline, Research Support, Non-U.S. Gov't, Review

Persistent link https://www.medvik.cz/link/pmid31119266

PubMed 31119266
DOI 10.1093/ehjcvp/pvz016
PII: 5497479
Knihovny.cz E-resources

Keywords
Atrial fibrillation, CHA2DS2-VASc score, Intermediate risk, Anticoagulation,
MeSH
Anticoagulants administration & dosage adverse effects MeSH
Administration, Oral MeSH
Stroke diagnosis epidemiology prevention & control MeSH
Atrial Fibrillation diagnosis drug therapy epidemiology MeSH
Risk Assessment MeSH
Clinical Decision-Making MeSH
Consensus MeSH
Hemorrhage chemically induced MeSH
Humans MeSH
Decision Support Techniques MeSH
Risk Factors MeSH
Treatment Outcome MeSH
Check Tag
Humans MeSH
Publication type
Journal Article MeSH
Research Support, Non-U.S. Gov't MeSH
Review MeSH
Practice Guideline MeSH
Names of Substances
Anticoagulants MeSH

Oral anticoagulation in patients presenting with non-valvular atrial fibrillation and a CHA2DS2-VASc score of 1 (CHA2DS2-VASc of 2 in women) remains a challenging approach in clinical practice. Therapeutic decisions need to balance the individual benefit of reducing thromboembolic risk against the potential harm due to an increase in bleeding risk in this intermediate risk patient population. Within the current opinion statement of the European Society of Cardiology working group of cardiovascular pharmacotherapy and the European Society of Cardiology council on stroke the currently available evidence on the anti-thrombotic management in patients presenting with a CHA2DS2-VASc of 1 is summarized. Easily applicable tools for a personalized refinement of the individual thromboembolic risk in patients with atrial fibrillation and a CHA2DS2-VASc score of 1 that guide clinicians through the question whether to anticoagulate or not are provided.

Atherosclerosis Research Unit Medical and Surgical Sciences Department Sant'Orsola Malpighi Hospital University of Bologna Via Zamboni 33 40126 Comune di Bologna BO Italy

BIH Center for Regenerative Therapies Charité Universitaetsmedizin Berlin Charitéplatz 1 10117 Berlin Germany

Cardiocenter 3rd Faculty of Medicine Charles University Opletalova 38 110 00 Staré Město Prague Czech Republic

Cardiology Division Department of Medicine Karolinska Institute Karolinska University Hospital Eugeniavägen 3 171 76 Solna Stockholm Sweden

Cardiology Pasing Institutstraße 14 81241 Munich Germany

Department of Cardiology Aalborg University Hospital Fredrik Bajers Vej 5 9100 Aalborg Denmark

Department of Cardiology Copenhagen University Hospital Blegdamsvej 9 2100 Copenhagen Denmark

Department of Cardiology Oslo University Hospital and Institute of Clinical Medicine Oslo University Klaus Torgírds vei 3 0372 Oslo Norway

Department of Cardiology Oudenarder Straße 16 13316 Berlin Germany

Department of Health Science and Technology The Faculty of Medicine Aalborg University Fredrik Bajers Vej 5 9100 Aalborg Denmark

Department of Health Sciences and Technology Aalborg University Fredrik Bajers Vej 5 9100 Aalborg Denmark

Department of Internal Medicine Cardiology and Nephrology Landesklinikum Wiener Neustadt Corvinusring 3 5 2700 Wiener Neustadt Austria