Collection of Excretory/Secretory Products from Individual Developmental Stages of the Blood Fluke Schistosoma mansoni
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
- Keywords
- Developmental stages, Excretory/secretory products, Schistosoma mansoni,
- MeSH
- Cercaria physiology MeSH
- Liver parasitology MeSH
- Mice MeSH
- Specimen Handling methods MeSH
- Ovum physiology MeSH
- Schistosoma mansoni growth & development metabolism MeSH
- Life Cycle Stages * MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
Individual developmental stages of blood fluke Schistosoma mansoni excrete or secrete a different set of molecules. Here we describe optimized protocols for collection of excretory/secretory products (E/S products) from cercariae, schistosomula, adult worms, and eggs. These E/S products are essential for successful parasitism functioning at the host-parasite interface, enabling invasion into the host and contributing to the survival of the parasite by modulation of host physiology and immune responses. Collection of sufficient amounts of E/S products is required for detailed research of these processes.
1st Faculty of Medicine Charles University Prague Czech Republic
Department of Parasitology Faculty of Science Charles University Prague Czech Republic
Institute of Organic Chemistry and Biochemistry Czech Academy of Sciences Prague Czech Republic
Institute of Specific Prophylaxis and Tropical Medicine Medical University of Vienna Vienna Austria
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