AIMS: The aim of this study is to establish the prevalence of diabetes (DM) and prediabetes in the Czech population aged 25-64 years and to evaluate the relationships with various cardiometabolic, sociodemographic, and lifestyle risk factors. METHODS: This was an epidemiological study with a stratified, crosssectional, random sampling design. Sociodemographic, lifestyle, and anamnestic data were collected through interviewer-administered questionnaires, medical examination, and biochemical assays. RESULTS: Among the 1189 participants, 114 were diagnosed with DM (9.6%), 330 with prediabetes (27.8%) and 745 were non-diabetes/non-prediabetes individuals (62.7%). Logistic regression analysis showed that overweight, general and abdominal obesity, hypertension, and lower level of HDL (increased risk) significantly increased the risk of both prediabetes and DM, while living in the cities diminished risk of DM. Among lifestyle variables the significant increased risk of prediabetes and DM was found for smokers and ex-smokers. In other lifestyle variables (marijuana lifetime prevalence, physical activity and frequency of alcohol drinking) the significantly higher or lower risk for prediabetes or DM was not found. CONCLUSIONS: The study shows a high prevalence of DM and prediabetes in the Czech population of age between 25 and 64, providing data on their association with several risk factors.

Arbeitsgemeinschaft der Belegärzte am Alice Hospital 64287 Darmstadt Germany

Center for Research of Diabetes Metabolism and Nutrition Ruská 97 110 00 Prague Czech Republic; 2nd Department of Internal Medicine University Hospital Královské Vinohrady and 3rd Faculty of Medicine Ruská 97 110 00 Prague Czech Republic

Department of Internal Medicine University Hospital Motol 2nd Faculty of Medicine Charles University 5 Úvalu 84 150 00 Prague Czech Republic

Department of Social Geography and Regional Development Faculty of Science Charles University Albertov 6 128 00 Prague Czechia

Department of Social Geography and Regional Development Faculty of Science Charles University Albertov 6 128 00 Prague Czechia; National Institute of Public Health Šrobárova 48 100 00 Prague Czechia

Institute of Computer Science Academy of Science of the Czech Republic v v i Národní 3 117 20 Prague Czech Republic

National Institute of Public Health Šrobárova 48 100 00 Prague Czechia

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