Determination of amino acids by capillary and microchip electrophoresis with contactless conductivity detection - Theory, instrumentation and applications
Language English Country Netherlands Media print-electronic
Document type Journal Article, Review
PubMed
33379123
DOI
10.1016/j.talanta.2020.121922
PII: S0039-9140(20)31213-3
Knihovny.cz E-resources
- Keywords
- Amino acid, Capillary electrophoresis, Clinical analysis, Contactless conductivity detection, Food analysis, Microchip electrophoresis, Microdialysis, Sample treatment, Stacking,
- MeSH
- Amino Acids MeSH
- Electric Conductivity MeSH
- Electrophoresis, Capillary MeSH
- Electrophoresis, Microchip * MeSH
- Capillaries MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Amino Acids MeSH
This review article summarises aspects of the determination of amino acids using capillary and chip electrophoresis in combination with contactless conductivity detection from their historical beginnings to the present time. Discussion is included of the theory of conductivity detection in electromigration techniques, the design of contactless conductivity cells for detection in capillaries and on microchips, including the use of computer programs for simulation of the conductivity response and the process of the electrophoretic separation of amino acids. Emphasis is placed on optimisation of the background electrolyte composition, chiral separation, multidimensional separation, stacking techniques and the use of multidetection systems. There is also a description of clinical applications, the determination of amino acids in foodstuffs, waters, soils and composts with emphasis on modern techniques of sample treatment, such as microdialysis, liquid membrane extraction and many other techniques.
References provided by Crossref.org
Microdialysis as a tool for antibiotic assessment in patients with diabetic foot: a review
Development of CE-C4D Method for Determination Tropane Alkaloids
