National strategies for vaccination against COVID-19 in people living with HIV in Central and Eastern European region

. 2022 May ; 23 (5) : 546-552. [epub] 20211026

Jazyk angličtina Země Anglie, Velká Británie Médium print-electronic

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid34704331

INTRODUCTION: People living with HIV (PLWH) are at higher risk of poorer COVID-19 outcomes. Vaccination is a safe and effective method of prevention against many infectious diseases, including COVID-19. Here we investigate the strategies for national COVID-19 vaccination programmes across central and eastern Europe and the inclusion of PLWH in vaccination programmes. METHODS: The Euroguidelines in Central and Eastern Europe Network Group consists of experts in the field of infectious diseases from 24 countries in the region. Between 1 November 2020 and 19 March 2021 the group proceeded an on-line survey consisting of 20 questions. RESULTS: Twenty-two countries (out of 24 invited) participated in the survey and 20/22 countries in the period between December 2020 and March 2021 had already started their COVID-19 vaccination programme. In total, seven different vaccines were used by participating countries. In 17/21 countries (81%), vaccinated persons were centralized within the national registry. In 8/21 countries (38%) PLWH were prioritized for vaccination (the Czech Republic, Greece, Hungary, Lithuania, Montenegro, Romania, Slovakia, Slovenia) and the Czech Republic, Greece and Serbia had put in place national guidelines for vaccination of PLWH. In 14/20 countries (70%) vaccination was only provided by designated centres. Eighteen respondents (18/21; 85.7%) reported that they planned to follow up HIV patients vaccinated against COVID-19, mainly by measuring antibody levels and checking COVID-19 incidence (11/21; 52.3%). CONCLUSIONS: This survey-based study suggests that there are significant differences in terms of prioritizing PLWH, the types of vaccines used, vaccination coverage, and the development and implementation of a vaccination programmes within the region. Regardless of heterogenicity and existing barriers within the region, systematic vaccination in PLWH should have the highest priority, especially in those with severe immunodeficiency, risk factors, and in the elderly, aiming for prompt and high vaccination coverage.

Central Research Institute of Epidemiology Moskov Russia

Clinic for Infectious Diseases Clinical Center of Sarajevo University Sarajevo Bosnia and Herzegovina

Department for AIDS Specialized Hospital for Active Treatment of Infectious and Parasitic Disease Sofia Sofia Bulgaria

Department of Adults' Infectious Diseases Hospital for Infectious Diseases Medical University of Warsaw Warsaw Poland

Department of Infectious Diseases 1st Faculty of Medicine Charles University Prague and Faculty Hospital Bulovka Prague Czech Republic

Department of Infectious Diseases University Medical Center Ljubljana Ljubljana Slovenia

Department of Infectology and Geographical Medicine Center for Treatment of HIV AIDS Patients Academic L Dérer's University Hospital Bratislava Slovakia

Department of Pharmacology Clinical Pharmacology and Toxicology School of Medicine; University of Belgrade Belgrade Serbia

Ege University Izmir Turkey

Infectious Diseases AIDS and Clinical Immunology Center Tbilisi Georgia

Institute for Public Health of Montenegro Podgorica Montenegro

National Center for Disease Control and Prevention Yerevan Armenia

National Institute of Hematology and Infectious Diseases South Pest Central Hospital National Center of HIV Budapest Hungary

Republican Scientific and Practical Center for Medical Technologies Global Fund Grant Management Department Minsk Belarus

University General Hospital Attikon Medical School National and Kapodistrian University of Athens Athens Greece

University Hospital Center of Tirana Infectious Disease Service Tirana Albania

University Hospital for Infectious Diseases Zagreb Croatia

USMF Nicolae Testemitanu Chisinau Moldova

Victor Babes Clinical Hospital for Infectious and Tropical Diseases Bucharest Romania

Vilnius University Faculty of Medicine Vilnius University Hospital Santaros Klinikos Vilnius Lithuania

Viral Hepatitis and AIDS Department at the Gromashevsky Institute of Epidemiology and Infectious Diseases Kyiv Ukraine

West Tallinn Central Hospital Tallinn Estonia

Zobrazit více v PubMed

Cooper TJ, Woodward BL, Alom S, Harky A. Coronavirus disease 2019 (COVID‐19) outcomes in HIV/AIDS patients: a systematic review. HIV Med. 2020;21(9):567‐577. PubMed PMC

Bhaskaran K, Rentsch CT, MacKenna B, et al. HIV infection and COVID‐19 death: a population‐based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform. Lancet HIV. 2021;8(1):e24‐e32. PubMed PMC

Geretti AM, Stockdale AJ, Kelly SH, et al. Outcomes of COVID‐19 related hospitalization among people with HIV in the ISARIC WHO clinical characterization protocol (UK): a prospective observational study. Clin Infect Dis. 2020;73(7):e2095‐e2106. PubMed PMC

Bertagnolio S, Thwin SS, Silva R, et al. Clinical characteristi and prognostic factors in people living with HIV hospitalized with COVID‐19: findings from the WHO global clinical platform. IAS 2021. Abstract 2498.

Gao YD, Ding M, Dong X, et al. Risk factors for severe and critically ill COVID‐19 patients: a review. Allergy. 2021;76(2):428‐455. PubMed

Klonoff DC, Umpierrez GE. Letter to the editor: COVID‐19 in patients with diabetes: risk factors that increase morbidity. Metabolism. 2020;108:154224. PubMed PMC

Johnson KM, Belfer JJ, Peterson GR, Boelkins MR, Dumkow LE. Managing COVID‐19 in renal transplant recipients: a review of recent literature and case supporting corticosteroid‐sparing immunosuppression. Pharmacotherapy. 2020;40(6):517‐524. PubMed PMC

Hoffmann C, Casado JL, Harter G, et al. Immune deficiency is a risk factor for severe COVID‐19 in people living with HIV. HIV Med. 2021;22(5):372‐378. PubMed

Frater J, Ewer K, Ogbe A, et al. Safety and Immunogenicity of the ChAdox1 nCoV‐19 (AZD1222) Vaccine Against SARS‐CoV‐2 in HIV Infection. SSRN. DOI:10.2139/ssrn.3829931; https://ssrn.com/abstract=3829931. Accessed May 20, 2021. PubMed DOI PMC

Madhi S, Koen A & Fairlie L et al. ChAdOx1 nCoV‐19 (AZD1222) vaccine in people living with and without HIV. DOI:10.21203/rs.3.rs-322470/v1; https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3829931. Accessed March 17, 2021. PubMed DOI

BHIVA, DAIG, EACS, GESIDA, Polish Scientific AIDS Society and Portuguese Association for the clinical study of AIDS (APECS); Statement on risk of COVID‐19 for people living with HIV (PLWH) and SARS‐CoV‐2 vaccine advice for adults living with HIV; 2021. https://www.bhiva.org/joint‐statement‐on‐risk‐of‐COVID‐19‐for‐PLWH‐and‐SARS‐CoV‐2‐vaccine‐advice. Accessed April 15, 2021.

Polack FP, Thomas SJ, Kitchin N, et al. Safety and efficacy of the BNT162b2 mRNA covid‐19 vaccine. N Engl J Med. 2020;383(27):2603‐2615. PubMed PMC

Baden LR, El Sahly HM, Essink B, et al. Efficacy and safety of the mRNA‐1273 SARS‐CoV‐2 vaccine. N Engl J Med. 2021;384(5):403‐416. PubMed PMC

Buchbinder SP, McElrath MJ, Dieffenbach C, Corey L. Use of adenovirus type‐5 vectored vaccines: a cautionary tale. Lancet. 2020;396(10260):e68‐e69. PubMed PMC

Shinde V, Bhikha S, Hoosain Z, et al. Efficacy of NVX‐CoV2373 Covid‐19 vaccine against the B.1.351 variant. N Engl J Med. 2021;384(20):1899‐1909. PubMed PMC

Kowalska JD, Skrzat‐Klapaczynska A, Bursa D, et al. HIV care in times of the COVID‐19 crisis ‐ Where are we now in Central and Eastern Europe? Int J Infect Dis. 2020;96:311‐314. PubMed PMC

Kowalska JD, Kase K, Vassilenko A, et al. The characteristics of HIV‐positive patients with mild/asymptomatic and moderate/severe course of COVID‐19 disease‐A report from Central and Eastern Europe. Int J Infect Dis. 2021;104:293‐296. PubMed PMC

British HIV Association & Terrence Higgins Trust: COVID‐19 risk for people with HIV. https://www.bhiva.org/BHIVA‐and‐THT‐COVID‐19‐risk‐for‐people‐with‐HIV2020. Accessed June 5, 2021.

Del Amo J, Polo R, Moreno S, et al. Incidence and severity of COVID‐19 in HIV‐positive persons receiving antiretroviral therapy: a cohort study. Ann Intern Med. 2020;173(7):536‐541. PubMed PMC

Lee KW, Yap SF, Ngeow YF, Lye MS. COVID‐19 in people living with HIV: a systematic review and meta‐analysis. Int J Environ Res Public Health. 2021;18(7):3554. PubMed PMC

European Centre for Disease Prevention and Control . Overview of the implementation of COVID‐19 vaccination strategies adn deployment plans in the EU/EEA – 6 May 2021. ECDC: Stockholm; 2021. https://www.ecdc.europa.eu/en/publications‐data/overview‐implementation‐covid‐19‐vaccination‐strategies‐and‐vaccine‐deployment. Accessed May 8, 2021.

Jiang H, Zhou Y, Tang W. Maintaining HIV care during the COVID‐19 pandemic. Lancet HIV. 2020;7(5):e308‐e309. PubMed PMC

Czech national website on vaccination. https://onemocneni‐aktualne.mzcr.cz/vakcinace‐cr. Accessed March 19, 2021.

Hungarian national website on vaccination. https://koronavirus.gov.hu/. Accessed March 19, 2021.

Polish national website on vaccination. https://www.gov.pl/web/szczepimysie/szczepienie‐przeciwko‐covid‐19. Accessed March 19, 2021.

Slovakian national website on vaccination. https://www.korona.gov.sk/koronavirus‐na‐slovensku‐v‐cislach/. Accessed May 20, 2021.

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