The management of membranous nephropathy-an update
Jazyk angličtina Země Anglie, Velká Británie Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
Odkazy
PubMed
34748001
DOI
10.1093/ndt/gfab316
PII: 6423439
Knihovny.cz E-zdroje
- Klíčová slova
- calcineurin inhibitors, cyclophosphamide, membranous nephropathy, remission, rituximab,
- MeSH
- dospělí MeSH
- imunosupresiva terapeutické užití MeSH
- ledviny patologie MeSH
- lidé MeSH
- membranózní glomerulonefritida * diagnóza etiologie terapie MeSH
- pilotní projekty MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- imunosupresiva MeSH
In recent decades, several important advances have taken place in the understanding of the pathogenesis underlying membranous nephropathy (MN) that have sparked renewed interest in its management. Four landmark trials in MN and a fifth clinical trial-which was a pilot study-have been published in recent years. The results from some of these trials have had a significant impact on the recommendations included in the 2021 Kidney Disease: Improving Global Outcomes (KDIGO) Guideline for the Management of Glomerular Diseases, representing a significant step forward compared with the previous guideline in several aspects, including diagnosis, disease monitoring and treatment strategies. However, considering the rapidly evolving advances in the knowledge of MN and the recent publication of the STARMEN and RI-CYCLO trials, several recommendations contained in the guideline warrant updates. This article provides a perspective of the Immunonephrology Working Group of the European Renal Association regarding the management of MN in native kidneys of adult patients.
Department of Health Medicine and Caring Sciences Linköping University Linköping Sweden
Department of Internal Medicine 4 Hospital of the Ludwig Maximilians University Munich Germany
Department of Medicine University of Cambridge Cambridge UK
Department of Nephrology and Renal Transplantation Patras University Hospital Patras Greece
Department of Nephrology and Transplantation Queen Elizabeth University Hospital Glasgow UK
Department of Nephrology Hospital Universitario 12 de Octubre Madrid Spain
Department of Nephrology Hospital Universitario Fundacion Alcorcon Alcorcón Spain
Division of Nephrology Department of Internal Medicine Necmettin Erbakan University Konya Turkey
Division of Nephrology RWTH Aachen University Hospital Aachen Germany