The primate gut mycobiome-bacteriome interface is impacted by environmental and subsistence factors
Language English Country United States Media electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
35301322
PubMed Central
PMC8930997
DOI
10.1038/s41522-022-00274-3
PII: 10.1038/s41522-022-00274-3
Knihovny.cz E-resources
- MeSH
- Bacteria genetics MeSH
- Phylogeny MeSH
- Mycobiome * MeSH
- Primates MeSH
- Gastrointestinal Microbiome * MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
The gut microbiome of primates is known to be influenced by both host genetic background and subsistence strategy. However, these inferences have been made mainly based on adaptations in bacterial composition - the bacteriome and have commonly overlooked the fungal fraction - the mycobiome. To further understand the factors that shape the gut mycobiome of primates and mycobiome-bacteriome interactions, we sequenced 16 S rRNA and ITS2 markers in fecal samples of four different nonhuman primate species and three human groups under different subsistence patterns (n = 149). The results show that gut mycobiome composition in primates is still largely unknown but highly plastic and weakly structured by primate phylogeny, compared with the bacteriome. We find significant gut mycobiome overlap between captive apes and human populations living under industrialized subsistence contexts; this is in contrast with contemporary hunter-gatherers and agriculturalists, who share more mycobiome traits with diverse wild-ranging nonhuman primates. In addition, mycobiome-bacteriome interactions were specific to each population, revealing that individual, lifestyle and intrinsic ecological factors affect structural correspondence, number, and kind of interactions between gut bacteria and fungi in primates. Our findings indicate a dominant effect of ecological niche, environmental factors, and diet over the phylogenetic background of the host, in shaping gut mycobiome composition and mycobiome-bacteriome interactions in primates.
Anicoon Vétérinaires Ploemeur France
Bulindi Chimpanzee and Community Project Hoima Uganda
Callitrichid Research Center at the University of Nebraska at Omaha Omaha NE USA
Department of Animal Science University of Minnesota St Paul MN USA
Department of Anthropology Purdue University West Lafayette IN USA
Department of Biology University of Nebraska at Omaha Omaha NE USA
Department of Food Science and Nutrition University of Minnesota St Paul MN USA
Department of Food Science and Technology University of Nebraska Lincoln Lincoln NE USA
Institute of Vertebrate Biology Czech Academy of Sciences Brno Czech Republic
New York Consortium in Evolutionary Primatology New York NY USA
Prague Zoo Prague Czech Republic
Primate Microbiome Project University of Nebraska Lincoln Lincoln NE USA
WWF Central African Republic Bayanga Central African Republic
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