Anatomy of the pudendal nerve in clinically important areas: a pictorial essay and narrative review
Language English Country Germany Media print-electronic
Document type Journal Article, Review
PubMed
38240796
DOI
10.1007/s00276-023-03285-7
PII: 10.1007/s00276-023-03285-7
Knihovny.cz E-resources
- Keywords
- Anatomical variation, Entrapment, Pudendal nerve, Pudendal neuralgia, Sacrospinous ligament, Sacrotuberous ligament,
- MeSH
- Dissection MeSH
- Iatrogenic Disease MeSH
- Ligaments, Articular MeSH
- Humans MeSH
- Cadaver MeSH
- Pelvis MeSH
- Pudendal Nerve * anatomy & histology MeSH
- Pudendal Neuralgia * surgery MeSH
- Check Tag
- Humans MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
PURPOSE: The pudendal nerve is an anatomical structure arising from the ventral branches of the spinal roots S2-S4. Its complex course may be affected by surrounding structures. This may result in irritation or entrapment of the nerve with subsequent clinical symptoms. Aim of this study is to review the anatomy of the pudendal nerve and to provide detailed photographic documentation of the areas with most frequent clinical impact which are essential for surgical approach. METHODS: Major medical databases were searched to identify all anatomical studies investigating pudendal nerve and its variability, and possible clinical outcome of these variants. Extracted data consisted of morphometric parameters, arrangement of the pudendal nerve at the level of roots, formation of pudendal nerve, position according to sacrospinal and sacrotuberal ligaments and its terminal branches. One female cadaver hemipelvis was dissected with common variability of separate course of inferior rectal nerve. During dissection photodocumentation was made to record course of pudendal nerve with focus on areas with recorded pathologies and areas exposed to iatrogenic damage during surgical procedures. RESULTS: Narrative review was done to provide background for photodocumentation. Unique photos of course of the pudendal nerve was made in areas with great clinical significance. CONCLUSION: Knowledge of anatomical variations and course of the pudendal nerve is important for examinations and surgical interventions. Surgically exposed areas may become a site for iatrogenic damage of pudendal nerve; therefore, unique picture was made to clarify topographic relations.
See more in PubMed
Balaya V, Aubin A, Rogez JM, Douard R, Delmas V (2014) Le nerf dorsal du clitoris : de l’anatomie à la chirurgie reconstructrice du clitoris [The dorsal nerve of the clitoris: surgical applications]. Morphol bulletin de l’Association des anatomistes 98(320):8–17. https://doi.org/10.1016/j.morpho.2013.12.001 DOI
Barber MD, Bremer RE, Thor KB, Dolber PC, Kuehl TJ, Coates KW (2002) Innervation of the female levator ani muscles. Am J Obstet Gynecol 187(1):64–71. https://doi.org/10.1067/mob.2002.124844 PubMed DOI
Bergman RA, Thompson SA, Afifi AK, Saddeh FA (1988) Compendium of human anatomical variations. Urban and Schwarzenberg, Baltimore, pp 138–139
Cihak R (2011) Anatomie 3, 3rd edn. Grada Publishing, Prague, pp 607–608
Furtmüller GJ, McKenna CA, Ebmer J, Dellon AL (2014) Pudendal nerve 3-dimensional illustration gives insight into surgical approaches. Ann Plast Surg 73(6):670–678. https://doi.org/10.1097/SAP.0000000000000169 PubMed DOI
Gagnard C, Godlewski G, Prat D, Lan O, Cousineau J, Maklouf Y (1986) The nerve branches to the external anal sphincter: the macroscopic supply and microscopic structure. Surg Radiol Anat SRA 8(2):115–119. https://doi.org/10.1007/BF02421378 PubMed DOI
Ghanavatian S, Leslie SW, Derian A (2023) Pudendal nerve block. StatPearls Publishing, Treasure Island
Giulioni C, Asimakopoulos AD, Annino F, Garelli G, Riviere J, Piechaud-Kressmann J, Vuong NS, Lopez LH, Roche JB, Rouffilange J, Hoepffner JL, Galosi AB, Gaston RP, Piechaud T, Pierquet G (2023) First case-series of robot-assisted pudendal nerve release: technique and outcomes. Surg Endosc 37(7):5708–5713. https://doi.org/10.1007/s00464-023-10096-9 . (Epub 2023 May 19) PubMed DOI
Gleeson N, Baile W, Roberts WS, Hoffman M, Fiorica JV, Barton D, Cavanagh D (1994) Surgical and psychosexual outcome following vaginal reconstruction with pelvic exenteration. Eur J Gynaecol Oncol 15(2):89–95 PubMed
Gray H (2010) Gray’s anatomy, 15th edn. Barnes & Noble, Inc., New York, p 774
Gruber H, Kovacs P, Piegger J, Brenner E (2001) New, simple, ultrasound-guided infiltration of the pudendal nerve: topographic basics. Dis Colon Rectum 44(9):1376–1380. https://doi.org/10.1007/BF02234801 PubMed DOI
Habib N, Centini G, Klebanoff JS, Fernandes R, Giorgi M, Moawad GN, Bakar J (2023) Pudendal neuralgia: two case reports with laparoscopic nerve decompression. Facts Views Vis ObGyn 15(2):181–187. https://doi.org/10.52054/FVVO.15.2.073 PubMed DOI PMC
Hope EE, Bodensteiner JB, Thong N (1985) Neonatal lumbar plexus injury. Arch Neurol 42(1):94–95. https://doi.org/10.1001/archneur.1985.04060010104028 PubMed DOI
Hough DM, Wittenberg KH, Pawlina W, Maus TP, King BF, Vrtiska TJ, Farrell MA, Antolak SJ Jr (2003) Chronic perineal pain caused by pudendal nerve entrapment: anatomy and CT-guided perineural injection technique. AJR Am J Roentgenol 181(2):561–567. https://doi.org/10.2214/ajr.181.2.1810561 PubMed DOI
Hruby S, Ebmer J, Dellon AL, Aszmann OC (2005) Anatomy of pudendal nerve at urogenital diaphragm—new critical site for nerve entrapment. Urology 66(5):949–952. https://doi.org/10.1016/j.urology.2005.05.032 PubMed DOI
Jarragh A, Lari A, Shaikh M (2023) A computed tomography (CT) based morphometric study of superior pubic ramus anatomy among Arabs to determine safe intramedullary pubic rami screw insertion. Surg Radiol Anat SRA 45(5):603–609. https://doi.org/10.1007/s00276-023-03128-5 PubMed DOI
Kaur J, Leslie SW, Singh P (2023) Pudendal nerve entrapment syndrome. StatPearls Publishing, Treasure Island
Khoder W, Hale D (2014) Pudendal neuralgia. Obstet Gynecol Clin N Am 41(3):443–452. https://doi.org/10.1016/j.ogc.2014.04.002 DOI
Labat JJ, Riant T, Robert R, Amarenco G, Lefaucheur JP, Rigaud J (2008) Diagnostic criteria for pudendal neuralgia by pudendal nerve entrapment (Nantes criteria). Neurourol Urodyn 27(4):306–310. https://doi.org/10.1002/nau.20505 PubMed DOI
Lazarou G, Grigorescu BA, Olson TR, Downie SA, Powers K, Mikhail MS (2008) Anatomic variations of the pelvic floor nerves adjacent to the sacrospinous ligament: a female cadaver study. Int Urogynecol J Pelvic Floor Dysfunct 19(5):649–654. https://doi.org/10.1007/s00192-007-0494-6 PubMed DOI
Leibovitch I, Mor Y (2005) The vicious cycling: bicycling related urogenital disorders. Eur Urol 47(3):277–287. https://doi.org/10.1016/j.eururo.2004.10.024 PubMed DOI
Liu T, Wang S, Song J, Zhu H, Zhang J, Zhang P (2023) Application of periprostatic nerve block and pudendal nerve block in transrectal ultrasound-guided prostate biopsy. Altern Ther Health Med AT9283 (advance online publication)
Loukas M, Louis RG Jr, Hallner B, Gupta AA, White D (2006) Anatomical and surgical considerations of the sacrotuberous ligament and its relevance in pudendal nerve entrapment syndrome. Surg Radiol Anat SRA 28(2):163–169. https://doi.org/10.1007/s00276-006-0082-3 PubMed DOI
Mahakkanukrauh P, Surin P, Vaidhayakarn P (2005) Anatomical study of the pudendal nerve adjacent to the sacrospinous ligament. Clin Anat (New York, N.Y.) 18(3):200–205. https://doi.org/10.1002/ca.20084 DOI
Maldonado PA, Chin K, Garcia AA, Corton MM (2015) Anatomic variations of pudendal nerve within pelvis and pudendal canal: clinical applications. Am J Obstet Gynecol 213(5):727.e1-727.e7276. https://doi.org/10.1016/j.ajog.2015.06.009 PubMed DOI
Matejcík V (2010) Anatomical variations of lumbosacral plexus. Surg Radiol Anat SRA 32(4):409–414. https://doi.org/10.1007/s00276-009-0546-3 PubMed DOI
Matzel KE, Schmidt RA, Tanagho EA (1990) Neuroanatomy of the striated muscular anal continence mechanism. Implications for the use of neurostimulation. Dis Colon Rectum 33(8):666–673. https://doi.org/10.1007/BF02150742 PubMed DOI
Montoya TI, Calver L, Carrick KS, Prats J, Corton MM (2011) Anatomic relationships of the pudendal nerve branches. Am J Obstet Gynecol 205(5):504.e1-504.e5045. https://doi.org/10.1016/j.ajog.2011.07.014 PubMed DOI
Nanka O, Sedý J, Jarolím L (2007) Sulcus nervi dorsalis penis: site of origin of Alcock’s syndrome in bicycle riders? Med Hypotheses 69(5):1040–1045. https://doi.org/10.1016/j.mehy.2007.01.089 PubMed DOI
Necesalova P, Karbanova J, Rusavy Z, Pastor Z, Jansova M, Kalis V (2016) Mediolateral versus lateral episiotomy and their effect on postpartum coital activity and dyspareunia rate 3 and 6 months postpartum. Sex Reprod Healthc 8:25–30. https://doi.org/10.1016/j.srhc.2016.01.004 PubMed DOI
Nichols DH (1978) Effects of pelvic relaxation on gynecologic urologic problems. Clin Obstet Gynecol 21(3):759–774. https://doi.org/10.1097/00003081-197809000-00012 PubMed DOI
Obach J, Aragones JM, Ruano D (1983) The infrapiriformis foramen syndrome resulting from intragluteal injection. J Neurol Sci 58(1):135–142. https://doi.org/10.1016/0022-510x(83)90116-8 PubMed DOI
O’Bichere A, Green C, Phillips RK (2000) New, simple approach for maximal pudendal nerve exposure: anomalies and prospects for functional reconstruction. Dis Colon Rectum 43(7):956–960. https://doi.org/10.1007/BF02237358 PubMed DOI
Oelhafen K, Shayota BJ, Muhleman M, Klaassen Z, Tubbs RS, Loukas M (2013) Benjamin Alcock (1801-?) and his canal. Clin Anat (New York, N.Y.) 26(6):662–666. https://doi.org/10.1002/ca.22080 DOI
O’Rahilly R, Müller F, Meyer DB (1990) The human vertebral column at the end of the embryonic period proper. 4. The sacrococcygeal region. J Anat 168:95–111 PubMed PMC
Pirro N, Sielezneff I, Le Corroller T, Ouaissi M, Sastre B, Champsaur P (2009) Surgical anatomy of the extrapelvic part of the pudendal nerve and its applications for clinical practice. Surg Radiol Anat SRA 31(10):769–773. https://doi.org/10.1007/s00276-009-0518-7 PubMed DOI
Ploteau S, Perrouin-Verbe MA, Labat JJ, Riant T, Levesque A, Robert R (2017) Anatomical variants of the pudendal nerve observed during a transgluteal surgical approach in a population of patients with pudendal neuralgia. Pain Physician 20(1):E137–E143 PubMed DOI
Randall CL, Nichols DH (1971) Surgical treatment of vaginal inversion. Obstet Gynecol 38(3):327–332 PubMed
Robert R, Prat-Pradal D, Labat JJ, Bensignor M, Raoul S, Rebai R, Leborgne J (1998) Anatomic basis of chronic perineal pain: role of the pudendal nerve. Surg Radiol Anat SRA 20(2):93–98. https://doi.org/10.1007/BF01628908 PubMed DOI
Roberts WH, Taylor WH (1973) Inferior rectal nerve variations as it relates to pudendal block. Anat Rec 177(3):461–463. https://doi.org/10.1002/ar.1091770310 PubMed DOI
Sedý J, Nanka O, Belisová M, Walro JM, Jarolím L (2006) Sulcus nervi dorsalis penis/clitoridis: anatomic structure and clinical significance. Eur Urol 50(5):1079–1085. https://doi.org/10.1016/j.eururo.2006.02.024 PubMed DOI
Shafik A, Doss SH (1999) Pudendal canal: surgical anatomy and clinical implications. Am Surg 65(2):176–180 PubMed DOI
Shafik A, El-Sherif M, Youssef A, Olfat ES (1995) Surgical anatomy of the pudendal nerve and its clinical implications. Clin Anat (New York, N.Y.) 8(2):110–115. https://doi.org/10.1002/ca.980080205 DOI
Schraffordt SE, Tjandra JJ, Eizenberg N, Dwyer PL (2004) Anatomy of the pudendal nerve and its terminal branches: a cadaver study. ANZ J Surg 74(1–2):23–26. https://doi.org/10.1046/j.1445-1433.2003.02885.x PubMed DOI
Soucy B, Luong DH, Michaud J, Boudier-Revéret M, Sobczak S (2020) Accuracy of ultrasound-guided pudendal nerve block in the ischial spine and Alcock’s canal levels: a cadaveric study. Pain Med (Malden, Mass.) 21(11):2692–2698. https://doi.org/10.1093/pm/pnaa136 DOI
Uzan C, Marchand F, Schmidt M, Meningaud JP, Hersant B (2020) Clitoral reduction: technical note. Ann Chir Plast Esthet 65(4):e7–e13. https://doi.org/10.1016/j.anplas.2019.10.002 PubMed DOI