The Effect of Two Somatic-Based Practices Dance and Martial Arts on Irisin, BDNF Levels and Cognitive and Physical Fitness in Older Adults: A Randomized Control Trial
Jazyk angličtina Země Nový Zéland Médium electronic-ecollection
Typ dokumentu časopisecké články, randomizované kontrolované studie
PubMed
39525874
PubMed Central
PMC11550684
DOI
10.2147/cia.s482479
PII: 482479
Knihovny.cz E-zdroje
- Klíčová slova
- ageing, biomarkers, cognitive domains, cognitive function, cognitive performance, serum,
- MeSH
- afekt MeSH
- bojové sporty * fyziologie MeSH
- fibronektiny * krev MeSH
- kognice * MeSH
- lidé MeSH
- mozkový neurotrofický faktor * krev MeSH
- senioři MeSH
- tanec * fyziologie MeSH
- tělesná výkonnost * fyziologie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- randomizované kontrolované studie MeSH
- Názvy látek
- BDNF protein, human MeSH Prohlížeč
- fibronektiny * MeSH
- FNDC5 protein, human MeSH Prohlížeč
- mozkový neurotrofický faktor * MeSH
BACKGROUND: Maintaining healthy brain function during ageing is of great importance, especially for the self-sufficiency of older adults. The main aim of this study was to determine the effects of dance and martial arts on exerkines Brain Derived Neurotrophic Factor (BDNF) and irisin blood serum levels. METHODS: This randomized controlled trial examined the effects of dance and martial arts on serum Brain-Derived Neurotrophic Factor (BDNF) and irisin levels, as well as cognitive function, mood, and physical measures in older adults. Seventy-seven independently living older adults (mean age 70.3±3.8 years) were randomized into three groups: dance (DG), martial arts (MaG), and control (CG), followed over 12 weeks. Generalized linear models were used to assess the interventions' effects. RESULTS: There was a significant increase in BDNF levels in both the DG (1.8 ± 4.9, p < 0.05) and MaG (3.5 ± 6.3, p < 0.05), while CG experienced a decrease (-4.9 ± 8.2, p < 0.05). Between-group effects were significant for BDNF, with DG and MaG showing higher levels than CG (p < 0.05). No significant changes in irisin levels were found. Cognitive performance, particularly attention and mental flexibility (measured by the Trail Making Test A and B), significantly improved in the DG compared to CG (p < 0.05). Additionally, participants in DG showed improved mood based on the Geriatric Depression Scale (p < 0.05) compared to CG. Anthropometric T-scores were significantly associated with changes in irisin levels (p < 0.05) after intervention. CONCLUSION: The study found that dance and martial arts upregulated BDNF levels, with dance showing notable improvements in cognitive function and mood in older adults. Changes in anthropometric measures were linked to increased irisin levels. These findings suggest that both dance and martial arts may promote healthy brain function in aging populations. TRIAL REGISTRATION: NCT05363228.
3rd Faculty of Medicine Charles University Department of Neurology Prague Czech Republic
Department of Sports Dietetics Poznan University of Physical Education Poznań 61 871 Poland
Faculty of Physical Education and Sport Charles University Prague Czech Republic
University Hospital Kralovske Vinohrady Department of Neurology Prague Czech Republic
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