This report summarizes the ASEV-CzeSEV Joint Meeting on Extracellular Vesicles (EVs), held at the Medical University of Vienna in September 2024. The conference focused on introducing and expanding EV research and infrastructure within the Czech Republic and Austria, highlighting areas for collaboration. Key sessions featured research on EV-based diagnostics, tissue regeneration, interspecies communication and therapeutic applications, with an emphasis on shared resources and cross-border partnerships. The program included oral and poster presentations on EV engineering, new isolation techniques, and potential clinical applications, as well as industry updates on the latest EV technologies. The meeting concluded with awards for outstanding presentations reflecting the quality of work presented. Following the conference, a dedicated workshop was held on flow cytometry analysis of EVs, allowing participants to deepen their technical expertise in EV characterization. This report captures the main discussions, findings, and collaborative opportunities explored at the ASEV-CzeSEV meeting, signaling strong regional support for advancing EV research.

Austrian Cluster for Tissue Regeneration Vienna 1200 Austria

Department of Biophysics of Immune System Institute of Biophysics of the Czech Academy of Sciences Brno 612 00 Czech Republic

Department of Experimental Biology Faculty of Science Masaryk University Brno 625 00 Czech Republic

Department of Medicine 1 Division of Hematology and Hemostaseology Medical University of Vienna Vienna 1090 Austria

Department of Pathological Physiology Faculty of Medicine Masaryk University Brno 625 00 Czech Republic

Department of Pharmacology and Toxicology Veterinary Research Institute Brno 621 00 Czech Republic

Department of Radiodiagnostic and Interventional Radiology Institute for Clinical and Experimental Medicine Prague 140 21 Czech Republic

Institute of Specific Prophylaxis and Tropical Medicine Centre for Pathophysiology Infectiology and Immunology Medical University of Vienna Vienna 1091 Austria

International Clinical Research Center St Anne's University Hospital Brno Brno 602 00 Czech Republic

Ludwig Boltzmann Institute for Traumatology the Research Centre in Cooperation with AUVA Vienna 1200 Austria

Zobrazit více v PubMed

Giovanazzi A, van Herwijnen MJC, Kleinjan M, van der Meulen GN, Wauben MHM. Surface protein profiling of milk and serum extracellular vesicles unveils body fluid-specific signatures. Sci Rep. 2023;13:8758. doi: 10.1038/s41598-023-35799-w. PubMed DOI PMC

Webb PM, Jordan SJ. Global epidemiology of epithelial ovarian cancer. Nat Rev Clin Oncol. 2024;21:389–400. doi: 10.1038/s41571-024-00881-3. PubMed DOI

Sandanusova M, Turkova K, Pechackova E, et al. Growth phase matters: boosting immunity via Lacticasebacillus-derived membrane vesicles and their interactions with TLR2 pathways. J Extracell Biol. 2024;3:e169. doi: 10.1002/jex2.169. PubMed DOI PMC

Schmid AM, Razim A, Wysmołek M, et al. Extracellular vesicles of the probiotic bacteria E. coli O83 activate innate immunity and prevent allergy in mice. Cell Commun Signal. 2023;21:297. doi: 10.1186/s12964-023-01329-4. PubMed DOI PMC

Bobbili MR, Görgens A, Yan Y, et al. Snorkel-tag based affinity chromatography for recombinant extracellular vesicle purification. J Extracell Vesicles. 2024;13:e12523. doi: 10.1002/jev2.12523. PubMed DOI PMC