Surface plasmon resonance biosensors and their medical applications
Language English Country England, Great Britain Media print-electronic
Document type Journal Article, Review
PubMed
40037036
DOI
10.1016/j.bios.2025.117308
PII: S0956-5663(25)00182-4
Knihovny.cz E-resources
- Keywords
- Biomarker, Medical diagnostics, Optical biosensor, Plasmonic affinity biosensor, Surface plasmon resonance biosensor,
- MeSH
- Bacteria isolation & purification MeSH
- Biosensing Techniques * methods instrumentation MeSH
- Equipment Design MeSH
- Exosomes chemistry MeSH
- Humans MeSH
- Nucleic Acids analysis isolation & purification MeSH
- Surface Plasmon Resonance * methods instrumentation MeSH
- Proteins analysis MeSH
- Viruses isolation & purification MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Nucleic Acids MeSH
- Proteins MeSH
Surface plasmon resonance (SPR) biosensors are an advanced optical biosensing technology that has been widely used in molecular biology for the investigation of biomolecular interactions and in bioanalytics for the detection of biological species. This work aims to review progress in the development of SPR biosensors for medical diagnostics, focusing mainly on advances in optical platforms and assays enabling analysis of complex biological matrices. Applications of SPR biosensors for the detection of medically relevant analytes, such as nucleic acids, proteins, exosomes, viruses, bacteria, and circulating tumor cells, are also reviewed. The detection performance of current SPR biosensors is discussed, and routes for improving performance and expanding applications of SPR biosensors in medical diagnostics are outlined.
References provided by Crossref.org
