Proprotein Convertase 9 [proproteinkonvertasa subtilisin/kexin typu 9]
- Terms
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konvertáza 1 regulující apoptózu neuronů
NARC-1
PCSK9
proprotein konvertáza subtilisin/kexin typu 9
proproteinkonvertáza subtilisin/kexin typu 9
proproteinová konvertasa subtilisin/kexin typu 9
proproteinová konvertáza subtilisin/kexin typu 9
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NARC-1 Protein
Neural Apoptosis-Regulated Convertase 1
Proprotein Convertase, Subtilisin-Kexin Type 9
A proprotein convertase that is essential for CHOLESTEROL homeostasis. It binds to and is required for the lysosomal degradation of the LDL RECEPTOR (LDLR); the VLDL receptor, and the APOLIPOPROTEIN E RECEPTOR. It also regulates neuronal APOPTOSIS.
- DUI
- D000071449 MeSH Browser
- CUI
- M000614708
- Previous indexing
- Proprotein Convertases (2003-2016); Serine Endopeptidases (2003-2016)
- History note
- 2017
- Public note
- 2017
Combination
- antagonists & inhibitors
- PCSK9 Inhibitors
Allowable subheadings
- AD
- administration & dosage 26
- AE
- adverse effects 8
- AN
- analysis 3
- BI
- biosynthesis
- BL
- blood 5
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects 23
- EC
- economics 7
- GE
- genetics 13
- HI
- history
- IM
- immunology 5
- IP
- isolation & purification
- ME
- metabolism 8
- PK
- pharmacokinetics 8
- PD
- pharmacology 38
- PH
- physiology 5
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 128
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
PCSK9 protein, human Chemical MeSH Browser
PCSK9 protein, rat Chemical MeSH Browser
Pcsk9 protein, mouse Chemical MeSH Browser