Complement Factor I [komplement - faktor I]
topical
- Terms
-
C3b/C4b inaktivátor
inaktivátor C3b
inaktivátor C3b-C4b
-
C3b Inactivator
C3b-C4b Inactivator
C4b-C3b-INA
C4bC3bINA
Complement 3b-Complement 4b Inactivator
Complement C4b-C3b Inactivator
Persistent link
https://www.medvik.cz/link/D017244
Definition
A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein, respectively. It is a 66-kDa glycoprotein that converts C3b to inactivated C3b (iC3b) followed by the release of two fragments, C3c (150-kDa) and C3dg (41-kDa). It was formerly called KAF, C3bINF, or enzyme 3b inactivator.
- Annotation
- do not confuse with FACTOR I see FIBRINOGEN
- DUI
- D017244 MeSH Browser
- CUI
- M0026165
- Previous indexing
- Peptide Peptidohydrolases (1983-1987); Serine Proteinases (1988-1992)
- History note
- 93; was FACTOR I, C 3B INACTIVATOR (NM) 1983-92
- Online note
- use COMPLEMENT FACTOR I (NM) to search FACTOR I, C 3B INACTIVATOR 1983-92
- Public note
- 93; COMPLEMENT FACTOR I was indexed under SERINE PROTEINASES 1988-92 & under PEPTIDE PEPTIDOHYDROLASES 1983-87
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.277.656.300.760.210
Complement Factor I
D08.811.277.656.300.760.431
High-Temperature Requirement A Serine Peptidase 2
D08.811.277.656.300.760.646
Proprotein Convertase 2
D08.811.277.656.300.760.648
Proprotein Convertase 5
D08.811.277.656.300.760.753
Reelin Protein
D08.811.277.656.959.350.210
Complement Factor I
D08.811.277.656.959.350.431
High-Temperature Requirement A Serine Peptidase 2
D08.811.277.656.959.350.646
Proprotein Convertase 2
D08.811.277.656.959.350.648
Proprotein Convertase 5
D08.811.277.656.959.350.753
Reelin Protein
D12.776.124.486.274.920.325.210
Complement Factor I
CFI protein, human Chemical MeSH Browser