A patched receptor that may function redundantly with the PATCHED-1 RECEPTOR to modulate hedgehog signaling. It may also play a role in epidermal development and as a TUMOR SUPPRESSOR PROTEIN. Mutations in the patched-2 gene are associated with BASAL CELL NEVUS SYNDROME; CARCINOMA, BASAL CELL; and MEDULLOBLASTOMA.

DUI

D000072082 MeSH Prohlížeč

CUI

M000616307

Historická pozn.

2017 (1996)

Veřejná pozn.

2017; 2017; PATCHED-2 RECEPTOR was indexed under RECEPTORS, CELL SURFACE 2005-2016, and under MEMBRANE PROTEINS 1996-2005