Patched-2 Receptor [receptor Patched 2]

topical
Terms

Patched protein homolog 2
protein PTCH2

 

Patched Homolog-2
Patched Receptor-2
Patched-2 Protein
PTCH2 Protein

Definition

A patched receptor that may function redundantly with the PATCHED-1 RECEPTOR to modulate hedgehog signaling. It may also play a role in epidermal development and as a TUMOR SUPPRESSOR PROTEIN. Mutations in the patched-2 gene are associated with BASAL CELL NEVUS SYNDROME; CARCINOMA, BASAL CELL; and MEDULLOBLASTOMA.

DUI
D000072082 MeSH Browser
CUI
M000616307
History note
2017 (1996)
Public note
2017; 2017; PATCHED-2 RECEPTOR was indexed under RECEPTORS, CELL SURFACE 2005-2016, and under MEMBRANE PROTEINS 1996-2005

D Chemicals and Drugs
D12.776 Proteins 2 577
D12.776.543 Membrane Proteins 849
D12.776.543.750 Receptors, Cell Surface 511
D12.776.543.750.058 Patched Receptors
D12.776.543.750.058.250 Niemann-Pick C1 Protein 3
D12.776.543.750.058.500 Patched-1 Receptor 2
D12.776.543.750.058.750 Patched-2 Receptor
D12.776.624 Neoplasm Proteins 412
D12.776.624.776 Tumor Suppressor Proteins 265
D12.776.624.776.633 Patched Receptors
D12.776.624.776.633.250 Niemann-Pick C1 Protein 3
D12.776.624.776.633.500 Patched-1 Receptor 2
D12.776.624.776.633.750 Patched-2 Receptor

PTCH2 protein, human Chemical MeSH Browser

Ptch2 protein, mouse Chemical MeSH Browser