Ku Autoantigen [antigen Ku]

topical
5
Terms

antigen G22P1
Ku antigen
Ku heterodimer
protein Ku

 

G22P1 Antigen
Ku Antigen
Ku Autoantigen, 70 kDa
Ku Autoantigen, 80 kDa
Ku Heterodimer
Ku Protein
Ku70 Antigen
Ku80 Antigen
X-ray Repair Cross-Complementing Protein 5
X-ray Repair Cross-Complementing Protein 6
XRCC5 Protein
XRCC6 Protein

Definition

An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.

DUI
D000072200 MeSH Browser
CUI
M0138075
History note
2017 (1986)
Public note
2017; KU AUTOANTIGEN was indexed under DNA-BINDING PROTEINS and ANTIGENS, NUCLEAR 2003-2016; and under ANTIGENS, SURFACE 1986-1991 and NUCLEAR PROTEINS 1985-2003

D Chemicals and Drugs
D08.811 Enzymes 1 547
D08.811.277 Hydrolases 475
D08.811.277.040 Acid Anhydride Hydrolases 6
D08.811.277.040.025 Adenosine Triphosphatases 429
D08.811.277.040.025.159 DNA Helicases 63
D08.811.277.040.025.159.124 DnaB Helicases
D08.811.277.040.025.159.155 Ku Autoantigen 5
D08.811.277.040.025.159.186 Minichromosome Maintenance Proteins 4
D08.811.277.040.025.159.249 RecQ Helicases 17
D08.811.277.040.025.159.500 Xeroderma Pigmentosum Group D Protein 5
D08.811.399 Isomerases 18
D08.811.399.340 DNA Helicases 63
D08.811.399.340.124 DnaB Helicases
D08.811.399.340.155 Ku Autoantigen 5
D08.811.399.340.249 RecQ Helicases 17
D08.811.399.340.375 X-linked Nuclear Protein
D12.776 Proteins 2 575
D12.776.157 Carrier Proteins 546
D12.776.157.687.063 Apoptosis Inducing Factor 10
D12.776.157.687.157 CCCTC-Binding Factor 2
D12.776.157.687.173 Centromere Protein A 2
D12.776.157.687.188 Centromere Protein B
D12.776.157.687.375 DNA Topoisomerases, Type I 24
D12.776.157.687.438 DNA-Activated Protein Kinase 14
D12.776.157.687.485 Histones 368
D12.776.157.687.493 Ku Autoantigen 5
D12.776.157.687.495 MRE11 Homologue Protein 6
D12.776.157.687.497 NF-kappa B p52 Subunit 2
D12.776.157.687.575 Nitric Oxide Synthase Type II 75
D12.776.157.687.613 Telomerase 189
D12.776.157.687.650 Tumor Suppressor Protein p53 755
D12.776.157.687.750 Werner Syndrome Helicase 2
D12.776.260 DNA-Binding Proteins 556
D12.776.260.060 Adenovirus E2 Proteins 1
D12.776.260.120 CCCTC-Binding Factor 2
D12.776.260.123 Centromere Protein A 2
D12.776.260.125 Centromere Protein B
D12.776.260.197 Elongin
D12.776.260.254 G-Box Binding Factors
D12.776.260.312 HMGA Proteins 1
D12.776.260.356 HMGB Proteins 4
D12.776.260.400 Homeodomain Proteins 122
D12.776.260.420 I-kappa B Proteins 5
D12.776.260.525 Ku Autoantigen 5
D12.776.260.529 LIM-Homeodomain Proteins 5
D12.776.260.531 Liver X Receptors 5
D12.776.260.539 MRE11 Homologue Protein 6
D12.776.260.540 MutL Proteins
D12.776.260.556 MutS Proteins
D12.776.260.600 NF-kappa B 215
D12.776.260.605 NFI Transcription Factors 6
D12.776.260.623 Nucleobindins 3
D12.776.260.643 Orphan Nuclear Receptors 2
D12.776.260.655 POU Domain Factors 4
D12.776.260.695 Rad51 Recombinase 42
D12.776.260.700 Replication Protein A 12
D12.776.260.702 Replication Protein C 3
D12.776.260.703 Repressor Proteins 189
D12.776.260.704 Retinoblastoma Protein 52
D12.776.260.713 Smad Proteins 14
D12.776.260.716 SMARCB1 Protein 15
D12.776.260.719 SOX Transcription Factors 1
D12.776.260.725 T-Box Domain Proteins 14
D12.776.260.730 TCF Transcription Factors 3
D12.776.260.735 Telomere-Binding Proteins 24
D12.776.260.750 Toll-Like Receptor 9 16
D12.776.260.755 Trans-Activators 110
D12.776.260.760 Transcription Factor AP-2 1
D12.776.260.790 Tristetraprolin 2
D12.776.260.820 Tumor Suppressor Protein p53 755
D12.776.260.885 Tumor Protein p73 6
D12.776.660 Nuclear Proteins 452
D12.776.660.625 Antigens, Nuclear 11
D12.776.660.625.500 Ki-67 Antigen 126
D12.776.660.625.625 Ku Autoantigen 5
D12.776.660.625.750 snRNP Core Proteins 1
D12.776.660.720.063 Apoptosis Inducing Factor 10
D12.776.660.720.157 CCCTC-Binding Factor 2
D12.776.660.720.173 Centromere Protein A 2
D12.776.660.720.188 Centromere Protein B
D12.776.660.720.375 DNA Topoisomerases, Type I 24
D12.776.660.720.438 DNA-Activated Protein Kinase 14
D12.776.660.720.485 Histones 368
D12.776.660.720.493 Ku Autoantigen 5
D12.776.660.720.495 MRE11 Homologue Protein 6
D12.776.660.720.497 NF-kappa B p52 Subunit 2
D12.776.660.720.575 Nitric Oxide Synthase Type II 75
D12.776.660.720.613 Telomerase 189
D12.776.660.720.650 Tumor Suppressor Protein p53 755
D12.776.660.720.750 Werner Syndrome Helicase 2
D23.050 Antigens 1 131
D23.050.290 Antigens, Nuclear 11
D23.050.290.500 Ki-67 Antigen 126
D23.050.290.625 Ku Autoantigen 5
D23.050.290.875 snRNP Core Proteins 1