PTB-Associated Splicing Factor [sestřihový faktor PSF]

topical
Terms

protein SFPQ
SFPQ protein

 

Polypyrimidine Tract-Binding Protein-Associated Splicing Factor
PSF Splicing Factor
SFPQ Protein
Splicing Factor Proline-Glutamine Rich Protein

Definition

An RNA splicing factor that also binds DNA. It is essential for pre-mRNA spicing in the formation of early SPLICEOSOMES and catalytic step II. It binds specifically to polypyrimidine tracts in INTRONS and is involved in the regulation of ALTERNATIVE SPLICING by SIGNAL TRANSDUCTION PATHWAYS.

DUI
D000072670 MeSH Browser
CUI
M0214402
History note
2017 (1993)
Public note
2017; PTB-ASSOCIATED SPLICING FACTOR was indexed under RNA-BINDING PROTEINS 1993-2016

D Chemicals and Drugs
D12.776 Proteins 2 581
D12.776.157 Carrier Proteins 546
D12.776.157.725 RNA-Binding Proteins 158
D12.776.157.725.829 RNA Splicing Factors 26
D12.776.157.725.829.250 Polypyrimidine Tract-Binding Protein 2
D12.776.157.725.829.282 PTB-Associated Splicing Factor
D12.776.157.725.829.313 Ribonucleoprotein, U1 Small Nuclear 5
D12.776.157.725.829.344 Ribonucleoprotein, U2 Small Nuclear 11
D12.776.157.725.829.375 Ribonucleoprotein, U5 Small Nuclear 5
D12.776.157.725.829.500 Serine-Arginine Splicing Factors 11
D12.776.157.725.829.750 Splicing Factor U2AF 3
D12.776.157.725.829.875 T-Cell Intracellular Antigen-1 1
D12.776.260 DNA-Binding Proteins 561
D12.776.260.060 Adenovirus E2 Proteins 1
D12.776.260.120 CCCTC-Binding Factor 2
D12.776.260.123 Centromere Protein A 2
D12.776.260.125 Centromere Protein B
D12.776.260.197 Elongin
D12.776.260.254 G-Box Binding Factors
D12.776.260.312 HMGA Proteins 1
D12.776.260.356 HMGB Proteins 4
D12.776.260.400 Homeodomain Proteins 125
D12.776.260.420 I-kappa B Proteins 5
D12.776.260.525 Ku Autoantigen 5
D12.776.260.529 LIM-Homeodomain Proteins 5
D12.776.260.531 Liver X Receptors 5
D12.776.260.539 MRE11 Homologue Protein 8
D12.776.260.540 MutL Proteins
D12.776.260.556 MutS Proteins
D12.776.260.600 NF-kappa B 220
D12.776.260.605 NFI Transcription Factors 8
D12.776.260.623 Nucleobindins 3
D12.776.260.643 Orphan Nuclear Receptors 2
D12.776.260.655 POU Domain Factors 4
D12.776.260.695 Rad51 Recombinase 42
D12.776.260.700 Replication Protein A 12
D12.776.260.702 Replication Protein C 3
D12.776.260.703 Repressor Proteins 189
D12.776.260.704 Retinoblastoma Protein 52
D12.776.260.713 Smad Proteins 14
D12.776.260.716 SMARCB1 Protein 15
D12.776.260.719 SOX Transcription Factors 1
D12.776.260.725 T-Box Domain Proteins 14
D12.776.260.730 TCF Transcription Factors 3
D12.776.260.735 Telomere-Binding Proteins 24
D12.776.260.750 Toll-Like Receptor 9 16
D12.776.260.755 Trans-Activators 110
D12.776.260.760 Transcription Factor AP-2 1
D12.776.260.790 Tristetraprolin 2
D12.776.260.820 Tumor Suppressor Protein p53 762
D12.776.260.885 Tumor Protein p73 6
D12.776.664 Nucleoproteins 91
D12.776.664.962 RNA-Binding Proteins 158
D12.776.664.962.829 RNA Splicing Factors 26
D12.776.664.962.829.250 Polypyrimidine Tract-Binding Protein 2
D12.776.664.962.829.282 PTB-Associated Splicing Factor
D12.776.664.962.829.313 Ribonucleoprotein, U1 Small Nuclear 5
D12.776.664.962.829.344 Ribonucleoprotein, U2 Small Nuclear 11
D12.776.664.962.829.375 Ribonucleoprotein, U5 Small Nuclear 5
D12.776.664.962.829.500 Serine-Arginine Splicing Factors 11
D12.776.664.962.829.750 Splicing Factor U2AF 3
D12.776.664.962.829.875 T-Cell Intracellular Antigen-1 1