PTB-Associated Splicing Factor [sestřihový faktor PSF]
- Terms
-
protein SFPQ
SFPQ protein
-
Polypyrimidine Tract-Binding Protein-Associated Splicing Factor
PSF Splicing Factor
SFPQ Protein
Splicing Factor Proline-Glutamine Rich Protein
An RNA splicing factor that also binds DNA. It is essential for pre-mRNA spicing in the formation of early SPLICEOSOMES and catalytic step II. It binds specifically to polypyrimidine tracts in INTRONS and is involved in the regulation of ALTERNATIVE SPLICING by SIGNAL TRANSDUCTION PATHWAYS.
- DUI
- D000072670 MeSH Browser
- CUI
- M0214402
- History note
- 2017 (1993)
- Public note
- 2017; PTB-ASSOCIATED SPLICING FACTOR was indexed under RNA-BINDING PROTEINS 1993-2016
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine