KRIT1 Protein [protein KRIT1]

topical
Terms

Cerebral Cavernous Malformations 1 Protein
Krev Interaction Trapped Protein 1

Persistent link   https://www.medvik.cz/link/D000075927
Definition

A microtubule-associated protein consisting of four ANKYRIN REPEATS and a C-terminal FERM DOMAIN. It links the CYTOSKELETON to CELL JUNCTIONS via integrin cytoplasmic domain-associated protein-1 and plays an important role in regulating cell proliferation and integrity of endothelial cell junctions. It is also involved in REACTIVE OXYGEN SPECIES metabolism. Mutations in the KRIT1 gene are associated with type I CEREBRAL CAVERNOUS MALFORMATIONS.

DUI
D000075927 MeSH Browser
CUI
M000631688
Previous indexing
Proto-Oncogene Proteins (1997-2017); Microtubule-Associated Proteins (1997-2017)
History note
2018
Public note
2018

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 581
D12.776.220 Cytoskeletal Proteins 101
D12.776.220.600 Microtubule Proteins 22
D12.776.220.600.450 Microtubule-Associated Proteins 102
D12.776.220.600.450.100 Autophagy-Related Protein 8 Family 2
D12.776.220.600.450.125 Doublecortin Domain Proteins
D12.776.220.600.450.150 Dynactin Complex 1
D12.776.220.600.450.200 Dynamins 4
D12.776.220.600.450.325 Katanin 2
D12.776.220.600.450.450 Kinesins 38
D12.776.220.600.450.458 KRIT1 Protein
D12.776.220.600.450.465 Spastin
D12.776.220.600.450.480 Stathmin 4
D12.776.220.600.450.495 Survivin 6
D12.776.220.600.450.510 tau Proteins 218
D12.776.624 Neoplasm Proteins 413
D12.776.624.664 Oncogene Proteins 125
D12.776.624.664.700 Proto-Oncogene Proteins 264
D12.776.624.664.700.013 Axl Receptor Tyrosine Kinase
D12.776.624.664.700.025 Bcl-2-Like Protein 11 5
D12.776.624.664.700.037 c-Mer Tyrosine Kinase 2
D12.776.624.664.700.049 Chemokine CXCL1 7
D12.776.624.664.700.100 Cyclin D1 86
D12.776.624.664.700.110 Fibroblast Growth Factor 4 2
D12.776.624.664.700.112 Fibroblast Growth Factor 6
D12.776.624.664.700.114 fms-Like Tyrosine Kinase 3 53
D12.776.624.664.700.117 Janus Kinase 2 80
D12.776.624.664.700.119 KRIT1 Protein
D12.776.624.664.700.120 Kruppel-Like Factor 6 1
D12.776.624.664.700.123 Lipocalin-2 21
D12.776.624.664.700.128 Lymphocyte Specific Protein Tyrosine Kinase p56(lck) 10
D12.776.624.664.700.129 MDS1 and EVI1 Complex Locus Protein 2
D12.776.624.664.700.130 MutS Homolog 2 Protein 17
D12.776.624.664.700.148 Myeloid-Lymphoid Leukemia Protein 39
D12.776.624.664.700.158 N-Myc Proto-Oncogene Protein 9
D12.776.624.664.700.163 Pre-B-Cell Leukemia Transcription Factor 1 2
D12.776.624.664.700.165 B-Cell Lymphoma 3 Protein
D12.776.624.664.700.166 Proto-Oncogene Mas 3
D12.776.624.664.700.167 Proto-Oncogene Proteins c-abl 7
D12.776.624.664.700.168 Proto-Oncogene Proteins c-akt 120
D12.776.624.664.700.169 Proto-Oncogene Proteins c-bcl-2 148
D12.776.624.664.700.170 Proto-Oncogene Proteins c-bcl-6 3
D12.776.624.664.700.171 Proto-Oncogene Proteins c-bcr 19
D12.776.624.664.700.172 Proto-Oncogene Proteins c-cbl 6
D12.776.624.664.700.174 Proto-Oncogene Proteins c-crk 1
D12.776.624.664.700.175 Proto-Oncogene Proteins c-ets 19
D12.776.624.664.700.177 Proto-Oncogene Proteins c-fes
D12.776.624.664.700.179 Proto-Oncogene Proteins c-fos 62
D12.776.624.664.700.180 Proto-Oncogene Proteins c-fyn 4
D12.776.624.664.700.181 Proto-Oncogene Proteins c-hck 1
D12.776.624.664.700.182 Proto-Oncogene Proteins c-jun 18
D12.776.624.664.700.183 Proto-Oncogene Proteins c-kit 77
D12.776.624.664.700.184 Proto-Oncogene Proteins c-maf 1
D12.776.624.664.700.185 Proto-Oncogene Proteins c-mdm2 65
D12.776.624.664.700.186 Proto-Oncogene Proteins c-met 30
D12.776.624.664.700.187 Proto-Oncogene Proteins c-mos 2
D12.776.624.664.700.188 Proto-Oncogene Proteins c-myb 30
D12.776.624.664.700.189 Proto-Oncogene Proteins c-myc 67
D12.776.624.664.700.191 Proto-Oncogene Proteins c-pim-1 1
D12.776.624.664.700.192 Proto-Oncogene Proteins c-rel 2
D12.776.624.664.700.194 Proto-Oncogene Proteins c-ret 42
D12.776.624.664.700.195 Proto-Oncogene Proteins c-sis 3
D12.776.624.664.700.198 Proto-Oncogene Proteins c-vav 4
D12.776.624.664.700.199 Proto-Oncogene Proteins c-yes 1
D12.776.624.664.700.200 Proto-Oncogene Proteins p21(ras) 73
D12.776.624.664.700.202 Proto-Oncogene Proteins pp60(c-src) 7
D12.776.624.664.700.204 raf Kinases 70
D12.776.624.664.700.642 Receptor, ErbB-2 595
D12.776.624.664.700.790 Receptor, ErbB-3 9
D12.776.624.664.700.791 Receptor, ErbB-4
D12.776.624.664.700.792 Receptor, Fibroblast Growth Factor, Type 3 28
D12.776.624.664.700.800 Receptor, Macrophage Colony-Stimulating Factor 1
D12.776.624.664.700.815 Receptor, Notch4
D12.776.624.664.700.830 Receptors, Thyroid Hormone 40
D12.776.624.664.700.913 RNA-Binding Protein EWS 15
D12.776.624.664.700.915 RNA-Binding Protein FUS 6
D12.776.624.664.700.936 RUNX1 Translocation Partner 1 Protein
D12.776.624.664.700.957 Stathmin 4
D12.776.624.664.700.960 T-Cell Acute Lymphocytic Leukemia Protein 1
D12.776.624.664.700.962 Wnt-5a Protein 5
D12.776.624.664.700.967 Wnt1 Protein 4
D12.776.624.664.700.978 Wnt2 Protein
D12.776.624.664.700.989 Zinc Finger Protein GLI1 7
D12.776.631 Nerve Tissue Proteins 264
D12.776.631.560 Microtubule-Associated Proteins 102
D12.776.631.560.113 Doublecortin Protein 1
D12.776.631.560.225 Dynactin Complex 1
D12.776.631.560.338 Katanin 2
D12.776.631.560.450 Kinesins 38
D12.776.631.560.465 KRIT1 Protein
D12.776.631.560.480 Spastin
D12.776.631.560.510 tau Proteins 218

KRIT1 protein, human Chemical MeSH Browser

Krit1 protein, mouse Chemical MeSH Browser

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