Immunoglobulin G4-Related Disease [IgG4 asociovaná nemoc]

topical
26
Terms

IgG4 asociované onemocnění
IgG4-RD
onemocnění se vztahem k imunoglobulinu G4

 

IgG4 Related Systemic Disease
IgG4-Associated Autoimmune Disease
IgG4-RD
IgG4-Related Disease
IgG4-Related Kidney Disease
IgG4-Related Sclerosing Disease
Immunoglobulin G4-Related Kidney Disease
Immunoglobulin G4-Related Sclerosing Disease

Definition

A spectrum of systemic autoimmune diseases in which IMMUNOGLOBULIN G4 plays a pathophysiologic role. It can affect multiple organs in highly variable presentations, characterized by inflammatory lesions composed of IgG4-positive PLASMA CELLS, further infiltrated by T helper cells (T-LYMPHOCYTES, HELPER-INDUCER) when linked to progressive FIBROSIS and eventual organ damage.

DUI
D000077733 MeSH Browser
CUI
M000641392
Previous indexing
Autoimmune Diseases (2010-2018); Immunoglobulin G (2009-2018)
History note
2019
Public note
2019

C Diseases
C01 Infections 2 027
C04 Neoplasms 12 832
C11 Eye Diseases 1 495
C20.111 Autoimmune Diseases 1 940
C20.111.163 Addison Disease 129
C20.111.198 Arthritis, Juvenile 476
C20.111.199 Arthritis, Rheumatoid 3 132
C20.111.327 Diabetes Mellitus, Type 1 3 017
C20.111.555 Graves Disease 255
C20.111.730 Pemphigoid, Bullous 87
C20.111.736 Pemphigus 209