Synucleinopathies [synukleinopatie]
topical
28
- Terms
-
alfa-synukleinopatie
α-synukleinopatie
-
a-Synucleinopathies
alpha Synuclein Pathology
alpha-Synucleinopathies
Persistent link
https://www.medvik.cz/link/D000080874
Definition
Neurodegenerative disorders involving deposition of abnormal ALPHA-SYNUCLEIN in dopaminergic neurons and glial cells in the brain. Pathological aggregations of alpha-synuclein proteins results in LEWY BODIES and Lewy neurites; melanin granules in the SUBSTANTIA NIGRA and LOCUS COERULEUS; and glial cytoplasmic inclusions. Synucleinopathies are associated with mutation in the ALPHA-SYNUCLEIN (SNCA) gene on chromosome 4. PARKINSON DISEASE; LEWY BODY DISEASE with dementia; and MULTIPLE SYSTEM ATROPHY are prominent examples of synucleinopathy.
- DUI
- D000080874 MeSH Browser
- CUI
- M000648557
- Previous indexing
- alpha-Synuclein (1999-2019); Neurodegenerative Diseases (1998-2019)
- History note
- 2020
- Public note
- 2020
Allowable subheadings
- BL
- blood 2
- CF
- cerebrospinal fluid 1
- CI
- chemically induced
- CL
- classification 2
- CO
- complications 1
- CN
- congenital
- DI
- diagnosis 4
- DG
- diagnostic imaging 5
- DH
- diet therapy
- DT
- drug therapy
- EC
- economics
- EM
- embryology
- EN
- enzymology
- EP
- epidemiology
- EH
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- ET
- etiology 1
- GE
- genetics 2
- HI
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- immunology
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- MI
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- NU
- nursing
- PS
- parasitology
- PA
- pathology 4
- PP
- physiopathology 2
- PC
- prevention & control
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- psychology
- RT
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- RH
- rehabilitation
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- surgery
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- therapy
- UR
- urine
- VE
- veterinary
- VI
- virology
...
Occurrences in Medvik records