Complement C9 [komplement C9]
topical
- Terms
-
komplement 9
-
C9 Complement
Complement 9
Complement Component 9
Persistent link
https://www.medvik.cz/link/D003186
Definition
A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections.
- DUI
- D003186 MeSH Browser
- CUI
- M0004941
- Previous indexing
- Complement (1968-1974); Bacteriolysis (1966-1974); Hemolysis (1966-1974); specific cell
- History note
- 2006 (1975)
- Public note
- 2006; see COMPLEMENT 9 1978-2005, see COMPLEMENT 1975-1977
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D12.776.124.486.274.550
Complement C6
D12.776.124.486.274.650
Complement C7
D12.776.124.486.274.850
Complement C9
complement C9 polymer Chemical MeSH Browser
complement C9b Chemical MeSH Browser