Neuroleptic Malignant Syndrome [maligní neuroleptický syndrom]
- Terms
-
maligní neuroleptický syndrom vyvolaný neuroleptiky
neuroleptický maligní syndrom
-
Neuroleptic-Induced Neuroleptic Malignant Syndrome
Neuroleptic-Malignant Syndrome, Neuroleptic Induced
NMS (Neuroleptic Malignant Syndrome)
A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
- Annotation
- caused by tranquilizing agents so do not use /chem ind
- DUI
- D009459 MeSH Browser
- CUI
- M0014713
- Previous indexing
- Basal Ganglia Diseases (1979-1984); Fever (1966-1984); Malignant Hyperthermia (1973-1984); Muscle Rigidity (1972-1984); Tranquilizing Agents, Major (1975-1984)
- History note
- 1986(1985)
- Public note
- 1986; see BASAL GANGLIA DISEASES 1985
Allowable subheadings
- BL
- blood
- CF
- cerebrospinal fluid
- CL
- classification
- CO
- complications 4
- CN
- congenital
- DI
- diagnosis 31
- DG
- diagnostic imaging
- DH
- diet therapy
- DT
- drug therapy 13
- EC
- economics
- EM
- embryology
- EN
- enzymology
- EP
- epidemiology 1
- EH
- ethnology
- ET
- etiology 25
- GE
- genetics
- HI
- history
- IM
- immunology
- ME
- metabolism
- MI
- microbiology
- MO
- mortality
- NU
- nursing
- PS
- parasitology
- PA
- pathology 3
- PP
- physiopathology 4
- PC
- prevention & control
- PX
- psychology 1
- RT
- radiotherapy
- RH
- rehabilitation
- SU
- surgery
- TH
- therapy 22
- UR
- urine
- VE
- veterinary
- VI
- virology 1