Protein S Deficiency [nedostatek proteinu S]
- Terms
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deficience proteinu S
deficit proteinu S
protein S - nedostatek
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Deficiency, Protein S
Hereditary Thrombophilia Due To Protein S Deficiency
An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)
- DUI
- D018455 MeSH Browser
- CUI
- M0027690
- Previous indexing
- Glycoproteins/deficiency (1984-1992); Protein S/deficiency (1993-1994)
- History note
- 95
- Public note
- 95
Allowable subheadings
- BL
- blood
- CF
- cerebrospinal fluid
- CI
- chemically induced
- CL
- classification
- CO
- complications 1
- CN
- congenital
- DI
- diagnosis 2
- DG
- diagnostic imaging
- DH
- diet therapy
- DT
- drug therapy
- EC
- economics
- EM
- embryology
- EN
- enzymology
- EP
- epidemiology 1
- EH
- ethnology
- ET
- etiology
- GE
- genetics 2
- HI
- history
- IM
- immunology
- ME
- metabolism
- MI
- microbiology
- MO
- mortality
- NU
- nursing
- PS
- parasitology
- PA
- pathology
- PP
- physiopathology
- PC
- prevention & control
- PX
- psychology
- RT
- radiotherapy
- RH
- rehabilitation
- SU
- surgery
- TH
- therapy 1
- UR
- urine
- VE
- veterinary
- VI
- virology
Acquired Protein S Deficiency Disease MeSH Browser
Thrombophilia, Hereditary, Due To Protein S Deficiency, Autosomal Dominant Disease MeSH Browser
Thrombophilia, Hereditary, Due To Protein S Deficiency, Autosomal Recessive Disease MeSH Browser