Multiple Endocrine Neoplasia Type 1 [mnohočetná endokrinní neoplazie typu 1]

topical
16
Terms

MEN 1
MEN-1
nádory mnohočetné endokrinní typ 1
syndrom MEN 1
syndrom mnohočetné endokrinní adenomatózy - typ I
syndrom mnohočetné endokrinní neoplazie - MEN 1
Wermerův syndrom

 

Multiple Endocrine Neoplasia Type I
Multiple Endocrine Neoplasms Type 1
Neoplasia, Multiple Endocrine Type 1
Neoplasms, Multiple Endocrine Type 1
Neoplasms, Multiple Endocrine Type I
Wermer Syndrome

Persistent link   https://www.medvik.cz/link/D018761
Definition

A form of multiple endocrine neoplasia that is characterized by the combined occurrence of tumors in the PARATHYROID GLANDS, the PITUITARY GLAND, and the PANCREATIC ISLETS. The resulting clinical signs include HYPERPARATHYROIDISM; HYPERCALCEMIA; HYPERPROLACTINEMIA; CUSHING DISEASE; GASTRINOMA; and ZOLLINGER-ELLISON SYNDROME. This disease is due to loss-of-function of the MEN1 gene, a tumor suppressor gene (GENES, TUMOR SUPPRESSOR) on CHROMOSOME 11 (Locus: 11q13).

Annotation
coordinate IM with specific endocrine/neoplasm pre-coordinates (IM) + specific histological type (IM) if pertinent
DUI
D018761 MeSH Browser
CUI
M0028096
Previous indexing
Multiple Endocrine Neoplasia (1972-1994)
History note
95; MEA I, MEN I, & WERMER SYNDROME were see NEOPLASMS, MULTIPLE ENDOCRINE 1983-94
Online note
use MULTIPLE ENDOCRINE NEOPLASIA to search MEA I, MEN I, & WERMER SYNDROME 1983-94
Public note
95; MEA I, MEN I, & WERMER SYNDROME were see NEOPLASMS, MULTIPLE ENDOCRINE 1983-94

C Diseases
C04 Neoplasms 12 832