Paraneoplastic Cerebellar Degeneration [paraneoplastická cerebelární degenerace]

topical
11
Terms

paraneoplastická mozečková degenerace
paraneoplastická mozečková degenerace spojená s anti-Yo

 

Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration
Cerebellar Degeneration, Paraneoplastic
Cerebellar Syndrome, Paraneoplastic
Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated
Paraneoplastic Cerebellar Syndrome

Persistent link   https://www.medvik.cz/link/D020362
Definition

Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)

Annotation
coord with precoord organ/neopl term + histol type
DUI
D020362 MeSH Browser
CUI
M0328227
Previous indexing
Paraneoplastic Syndromes (1980-1999); Cerebellar Ataxia (1975-1999)
History note
2000
Public note
2000

C Diseases
C04 Neoplasms 12 774
C04.588.614.550.450 Limbic Encephalitis 28
C04.588.614.550.500 Myasthenia Gravis 418
C04.588.614.550.550 Myelitis, Transverse 24
C04.588.614.550.600 Opsoclonus-Myoclonus Syndrome 6
C04.588.614.550.700 Paraneoplastic Polyneuropathy 14
C04.730.856.437 Limbic Encephalitis 28
C04.730.856.490 Myasthenia Gravis 418
C04.730.856.543 Myelitis, Transverse 24
C10.228.140 Brain Diseases 1 178
C10.228.140.252 Cerebellar Diseases 165
C10.228.140.252.190 Cerebellar Ataxia 63
C10.228.140.252.200 Cerebellar Neoplasms 65
C10.228.140.252.300 Dandy-Walker Syndrome 6
C10.228.140.252.500 Miller Fisher Syndrome 12
C10.228.140.252.700 Spinocerebellar Degenerations 30
C10.574.781.550 Limbic Encephalitis 28
C10.574.781.588 Myasthenia Gravis 418
C10.574.781.625 Myelitis, Transverse 24