Integrin alpha4beta1 [integrin alfa4beta1]

topical
5
Terms

alpha4beta1 Integrin
CD49d-CD29
Integrin alpha(4)beta(1)
Integrin Heterodimer alpha4beta1
Very Late Activation Antigen-4
Very Late Antigen-4
VLA-4

Persistent link   https://www.medvik.cz/link/D039041
Definition

Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.

DUI
D039041 MeSH Browser
CUI
M0184906
Previous indexing
Integrins (1991-2002); Receptors, Lymphocyte Homing (1991-2002)
History note
2003 (1991)
Public note
2003; INTEGRIN ALPHA4BETA1 was indexed under INTEGRINS and RECEPTORS, LYMPHOCYTE HOMING 1991-2002

Allowable subheadings

AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors 1
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics 2
HI
history
IM
immunology 1
IP
isolation & purification
ME
metabolism
PH
physiology 2
RE
radiation effects
TU
therapeutic use
UL
ultrastructure

D Chemicals and Drugs
D09 Carbohydrates 723
D09.400 Glycoconjugates 58
D09.400.430 Glycoproteins 637
D09.400.430.890 Membrane Glycoproteins 200
D09.400.430.890.200 Cell Adhesion Molecules 309
D09.400.430.890.200.625 Receptors, Lymphocyte Homing 2
D09.400.430.890.200.625.144 Hyaluronan Receptors 60
D09.400.430.890.200.625.347 Integrin alpha4beta1 5
D09.400.430.890.200.625.550 Lymphocyte Function-Associated Antigen-1 7
D09.400.430.890.200.625.903 L-Selectin 8
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 577
D12.776.395 Glycoproteins 637
D12.776.395.550 Membrane Glycoproteins 200
D12.776.395.550.200 Cell Adhesion Molecules 309
D12.776.395.550.200.625 Receptors, Lymphocyte Homing 2
D12.776.395.550.200.625.144 Hyaluronan Receptors 60
D12.776.395.550.200.625.347 Integrin alpha4beta1 5
D12.776.395.550.200.625.550 Lymphocyte Function-Associated Antigen-1 7
D12.776.395.550.200.625.903 L-Selectin 8
D12.776.543 Membrane Proteins 849
D12.776.543.550 Membrane Glycoproteins 200
D12.776.543.550.200 Cell Adhesion Molecules 309
D12.776.543.550.200.625 Receptors, Lymphocyte Homing 2
D12.776.543.550.200.625.144 Hyaluronan Receptors 60
D12.776.543.550.200.625.347 Integrin alpha4beta1 5
D12.776.543.550.200.625.550 Lymphocyte Function-Associated Antigen-1 7
D12.776.543.550.200.625.903 L-Selectin 8
D12.776.543.750 Receptors, Cell Surface 511
D12.776.543.750.705 Receptors, Immunologic 129
D12.776.543.750.705.408 Integrins 118
D12.776.543.750.705.408.530 Receptors, Fibronectin 2
D12.776.543.750.705.408.530.249 Integrin alpha2beta1 3
D12.776.543.750.705.408.530.500 Integrin alpha4beta1 5
D12.776.543.750.705.408.530.750 Integrin alpha5beta1 3
D12.776.543.750.705.408.850 Receptors, Very Late Antigen
D12.776.543.750.705.408.850.099 Integrin alpha1beta1
D12.776.543.750.705.408.850.199 Integrin alpha2beta1 3
D12.776.543.750.705.408.850.249 Integrin alpha3beta1 1
D12.776.543.750.705.408.850.299 Integrin alpha4beta1 5
D12.776.543.750.705.408.850.349 Integrin alpha5beta1 3
D12.776.543.750.705.408.850.674 Integrin alpha6beta1
D12.776.543.750.705.877 Receptors, Lymphocyte Homing 2
D12.776.543.750.705.877.144 Hyaluronan Receptors 60
D12.776.543.750.705.877.347 Integrin alpha4beta1 5
D12.776.543.750.705.877.550 Lymphocyte Function-Associated Antigen-1 7
D12.776.543.750.705.877.903 L-Selectin 8
D23 Biological Factors 143
D23.050 Antigens 1 131
D23.050.301 Antigens, Surface 171
D23.050.301.350 Cell Adhesion Molecules 309
D23.050.301.350.625 Receptors, Lymphocyte Homing 2
D23.050.301.350.625.144 Hyaluronan Receptors 60
D23.050.301.350.625.347 Integrin alpha4beta1 5
D23.050.301.350.625.550 Lymphocyte Function-Associated Antigen-1 7
D23.050.301.350.625.903 L-Selectin 8

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