PTEN Phosphohydrolase [fosfohydroláza PTEN]

topical
50
Terms

fosfatasa PTEN
fosfohydrolasa PTEN
protein MMAC1
protein PTEN

 

MMAC1 Protein
Mutated In Multiple Advanced Cancers 1 Protein
Phosphatase and Tensin Homologue on Chromosome Ten Protein
PTEN Phosphatase
PTEN Protein
PTEN Protein Phosphatase

Persistent link   https://www.medvik.cz/link/D051059
Definition

A lipid phosphatase that contains a C2 DOMAIN and acts on phosphatidylinositol-3,4,5-trisphosphate to regulate various SIGNAL TRANSDUCTION PATHWAYS. It modulates CELL GROWTH PROCESSES; CELL MIGRATION; and APOPTOSIS. Mutations in PTEN are associated with COWDEN DISEASE and PROTEUS SYNDROME as well as NEOPLASTIC CELL TRANSFORMATION.

DUI
D051059 MeSH Browser
CUI
M0479128
History note
2006(1997)
Public note
2006; PTEN PROTEIN was indexed under PROTEIN-TYROSINE-PHOSPHATASES 1997-1998, under TUMOR SUPPRESSOR PROTEINS 1997-2005, & under PHOSPHORIC MONOESTER HYDROLASES 1999-2005

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis 1
AI
antagonists & inhibitors
BI
biosynthesis 2
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis 1
CH
chemistry 1
CL
classification
DF
deficiency 1
DE
drug effects
EC
economics
GE
genetics 37
HI
history
IM
immunology 2
IP
isolation & purification 1
ME
metabolism 13
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 1
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 551
D08.811.277 Hydrolases 475
D08.811.277.352 Esterases 207
D08.811.277.352.650 Phosphoric Monoester Hydrolases 154
D08.811.277.352.650.025 Acid Phosphatase 181
D08.811.277.352.650.030 ADP-Ribose 1''-Phosphate Phosphatases
D08.811.277.352.650.035 Alkaline Phosphatase 569
D08.811.277.352.650.200 Fructose-Bisphosphatase 7
D08.811.277.352.650.225 Glucose-6-Phosphatase 24
D08.811.277.352.650.300 Histidinol-Phosphatase
D08.811.277.352.650.575 4-Nitrophenylphosphatase 6
D08.811.277.352.650.587 Mitogen-Activated Protein Kinase Phosphatases 1
D08.811.277.352.650.600 Nucleotidases 29
D08.811.277.352.650.620 Phosphatidate Phosphatase 1
D08.811.277.352.650.622 Phosphofructokinase-2
D08.811.277.352.650.624 Phosphoinositide Phosphatases
D08.811.277.352.650.625 Phosphoprotein Phosphatases 23
D08.811.277.352.650.700 6-Phytase 7
D08.811.277.352.650.775 Protein Tyrosine Phosphatases 27
D08.811.277.352.650.850 PTEN Phosphohydrolase 50
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 581
D12.776.476 Intracellular Signaling Peptides and Proteins 175
D12.776.476.008 3',5'-Cyclic-AMP Phosphodiesterases 12
D12.776.476.009 3',5'-Cyclic-GMP Phosphodiesterases 2
D12.776.476.011 Activating Transcription Factor 6 3
D12.776.476.024 Adaptor Proteins, Signal Transducing 182
D12.776.476.050 Adenylyl Cyclases 160
D12.776.476.075 Apoptosis Regulatory Proteins 79
D12.776.476.081 Axin Signaling Complex 1
D12.776.476.156 Circadian Rhythm Signaling Peptides and Proteins 11
D12.776.476.175 Cold Shock Proteins and Peptides 3
D12.776.476.225 Cyclin-Dependent Kinase Inhibitor Proteins 44
D12.776.476.262 Cyclins 112
D12.776.476.265 Disks Large Homolog 4 Protein 1
D12.776.476.325 GTP-Binding Protein Regulators 16
D12.776.476.338 GTP-Binding Proteins 117
D12.776.476.350 Guanylate Cyclase 30
D12.776.476.381 I-kappa B Proteins 5
D12.776.476.383 Inhibitor of Growth Protein 1
D12.776.476.387 Intracellular Calcium-Sensing Proteins 2
D12.776.476.410 Mesothelin 2
D12.776.476.420 Methyl-Accepting Chemotaxis Proteins
D12.776.476.445 Mitogen-Activated Protein Kinase Phosphatases 1
D12.776.476.534 Mucin-4 5
D12.776.476.539 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.476.543 Olfactory Marker Protein
D12.776.476.555 Phosphatidylethanolamine Binding Protein
D12.776.476.556 Phosphatidylinositol 3-Kinases 126
D12.776.476.557 Phosphoinositide Phospholipase C 2
D12.776.476.559 Phosphoprotein Phosphatases 23
D12.776.476.561 Protein Phosphatase Inhibitory Proteins
D12.776.476.563 Protein Serine-Threonine Kinases 273
D12.776.476.564 Protein Tyrosine Phosphatases 27
D12.776.476.568 Protein-Tyrosine Kinases 622
D12.776.476.590 PTEN Phosphohydrolase 50
D12.776.476.650 RNA-Binding Protein EWS 15
D12.776.476.700 SAP90-PSD95 Associated Proteins
D12.776.476.800 Secreted Frizzled-Related Proteins
D12.776.476.900 Sirtuins 20
D12.776.476.932 Tuberous Sclerosis Complex 1 Protein 7
D12.776.476.935 Tuberous Sclerosis Complex 2 Protein 10
D12.776.476.938 Tumor Necrosis Factor alpha-Induced Protein 3 2
D12.776.476.941 Tumor Protein, Translationally-Controlled 1
D12.776.624 Neoplasm Proteins 413
D12.776.624.776 Tumor Suppressor Proteins 269
D12.776.624.776.010 Adenomatous Polyposis Coli Protein 13
D12.776.624.776.021 DCC Receptor
D12.776.624.776.051 Fanconi Anemia Complementation Group N Protein 4
D12.776.624.776.100 BRCA1 Protein 103
D12.776.624.776.101 BRCA2 Protein 97
D12.776.624.776.355 Cyclin-Dependent Kinase Inhibitor Proteins 44
D12.776.624.776.418 Cystatin M
D12.776.624.776.482 Deubiquitinating Enzyme CYLD 1
D12.776.624.776.503 Inhibitor of Growth Protein 1
D12.776.624.776.523 Kangai-1 Protein 1
D12.776.624.776.546 Kisspeptins 6
D12.776.624.776.610 Neurofibromin 1 14
D12.776.624.776.612 Neurofibromin 2 3
D12.776.624.776.633 Patched Receptors
D12.776.624.776.654 Promyelocytic Leukemia Protein 4
D12.776.624.776.695 PTEN Phosphohydrolase 50
D12.776.624.776.717 Retinoblastoma-Like Protein p107 4
D12.776.624.776.735 Retinoblastoma-Like Protein p130 5
D12.776.624.776.745 Retinoblastoma Protein 52
D12.776.624.776.760 Smad4 Protein 7
D12.776.624.776.766 Tuberous Sclerosis Complex 1 Protein 7
D12.776.624.776.769 Tuberous Sclerosis Complex 2 Protein 10
D12.776.624.776.772 Tumor Suppressor Protein p14ARF 4
D12.776.624.776.775 Tumor Suppressor Protein p53 762
D12.776.624.776.820 Tumor Protein p73 6
D12.776.624.776.865 Von Hippel-Lindau Tumor Suppressor Protein 31
D12.776.624.776.960 WT1 Proteins 30
D12.776.624.776.980 WW Domain-Containing Oxidoreductase 1

PTEN protein, Drosophila Chemical MeSH Browser

PTEN protein, human Chemical MeSH Browser

PTEN1 protein, Arabidopsis Chemical MeSH Browser

Pten protein, mouse Chemical MeSH Browser

Pten protein, pufferfish Chemical MeSH Browser

Pten protein, rat Chemical MeSH Browser

TAT-PTEN fusion protein Chemical MeSH Browser

TPTE protein, human Chemical MeSH Browser

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