Cortactin [kortaktin]

topical
1
Terms

cortactin

Persistent link   https://www.medvik.cz/link/D051356
Definition

A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organization. It is also an SH3 DOMAIN containing phosphoprotein, and it mediates tyrosine PHOSPHORYLATION based SIGNAL TRANSDUCTION by PROTO-ONCOGENE PROTEIN PP60(C-SRC).

DUI
D051356 MeSH Browser
CUI
M0214241
History note
2006(1983)
Public note
2006; CORTACTIN was indexed under MICROFILAMENT PROTEINS 1993-2005

Allowable subheadings

AD
administration & dosage 0
AE
adverse effects 0
AG
agonists 0
AN
analysis 0
AI
antagonists & inhibitors 0
BI
biosynthesis 0
BL
blood 0
CF
cerebrospinal fluid 0
CS
chemical synthesis 0
CH
chemistry 0
CL
classification 0
DF
deficiency 0
DE
drug effects 0
EC
economics 0
GE
genetics 0
HI
history 0
IM
immunology 0
IP
isolation & purification 0
ME
metabolism 1
PK
pharmacokinetics 0
PD
pharmacology 0
PH
physiology 0
PO
poisoning 0
RE
radiation effects 0
ST
standards 0
SD
supply & distribution 0
TU
therapeutic use 0
TO
toxicity 0
UL
ultrastructure 0
UR
urine 0

D Chemicals and Drugs
D05 Macromolecular Substances 103
D05.750 Polymers 1 053
D05.750.078 Biopolymers 96
D05.750.078.730 Microfilament Proteins 52
D05.750.078.730.032 Actin Capping Proteins 1
D05.750.078.730.212 Actin Depolymerizing Factors 5
D05.750.078.730.246 Actin-Related Protein 2-3 Complex 4
D05.750.078.730.248 Actinin 11
D05.750.078.730.250 Actins 292
D05.750.078.730.266 Calponins 1
D05.750.078.730.281 Cortactin 1
D05.750.078.730.315 Filamins 4
D05.750.078.730.333 Formins 2
D05.750.078.730.350 Gelsolin 5
D05.750.078.730.475 Myosins 132
D05.750.078.730.556 Myristoylated Alanine-Rich C Kinase Substrate
D05.750.078.730.637 Profilins 10
D05.750.078.730.719 Tensins 1
D05.750.078.730.800 Tropomyosin 23
D05.750.078.730.825 Troponin 263
D05.750.078.730.912 Wiskott-Aldrich Syndrome Protein Family 2
D12 Amino Acids, Peptides, and Proteins 16
D12.644 Peptides 1 380
D12.644.360 Intracellular Signaling Peptides and Proteins 174
D12.644.360.024 Adaptor Proteins, Signal Transducing 176
D12.644.360.024.050 14-3-3 Proteins 75
D12.644.360.024.065 A Kinase Anchor Proteins 1
D12.644.360.024.082 Angiomotins 1
D12.644.360.024.098 Arrestins 6
D12.644.360.024.131 CARD Signaling Adaptor Proteins 7
D12.644.360.024.264 Caveolin 1 14
D12.644.360.024.272 Caveolin 2 1
D12.644.360.024.280 Cortactin 1
D12.644.360.024.282 Crk-Associated Substrate Protein 7
D12.644.360.024.285 Death Domain Receptor Signaling Adaptor Proteins 5
D12.644.360.024.287 Discs Large Homolog 1 Protein
D12.644.360.024.288 Dishevelled Proteins 18
D12.644.360.024.290 GRB2 Adaptor Protein 3
D12.644.360.024.299 GRB7 Adaptor Protein
D12.644.360.024.300 GRB10 Adaptor Protein
D12.644.360.024.301 Insulin Receptor Substrate Proteins 6
D12.644.360.024.302 Interferon Regulatory Factors 11
D12.644.360.024.303 Interferon-Stimulated Gene Factor 3
D12.644.360.024.306 Kelch-Like ECH-Associated Protein 1 9
D12.644.360.024.309 Mediator Complex 5
D12.644.360.024.310 mTOR Associated Protein, LST8 Homolog
D12.644.360.024.311 Myeloid Differentiation Factor 88 16
D12.644.360.024.313 Nod Signaling Adaptor Proteins 1
D12.644.360.024.314 Nuclear Receptor Coactivators 6
D12.644.360.024.315 Nuclear Receptor Interacting Protein 1 3
D12.644.360.024.316 Paxillin 5
D12.644.360.024.318 PII Nitrogen Regulatory Proteins
D12.644.360.024.319 Protein Inhibitors of Activated STAT 3
D12.644.360.024.320 Proto-Oncogene Proteins c-crk 1
D12.644.360.024.321 Proto-Oncogene Proteins c-vav 4
D12.644.360.024.322 Rabphilin-3A
D12.644.360.024.323 Rapamycin-Insensitive Companion of mTOR Protein 2
D12.644.360.024.324 Regulatory-Associated Protein of mTOR
D12.644.360.024.328 Retinoblastoma Binding Proteins 3
D12.644.360.024.329 Sequestosome-1 Protein 3
D12.644.360.024.330 Shc Signaling Adaptor Proteins
D12.644.360.024.332 Signaling Lymphocytic Activation Molecule Associated Protein
D12.644.360.024.334 Smad Proteins 14
D12.644.360.024.342 STAT Transcription Factors 23
D12.644.360.024.374 Suppressor of Cytokine Signaling Proteins 11
D12.644.360.024.437 Syntenins 2
D12.644.360.024.469 Transcriptional Coactivator with PDZ-Binding Motif Proteins 1
D12.644.360.024.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 4
D12.644.360.024.750 YAP-Signaling Proteins 5
D12.776 Proteins 2 575
D12.776.157 Carrier Proteins 546
D12.776.157.057 Adaptor Proteins, Signal Transducing 176
D12.776.157.057.001 5-Lipoxygenase-Activating Proteins 1
D12.776.157.057.002 14-3-3 Proteins 75
D12.776.157.057.003 A Kinase Anchor Proteins 1
D12.776.157.057.005 Arrestins 6
D12.776.157.057.006 CARD Signaling Adaptor Proteins 7
D12.776.157.057.010 Caveolin 1 14
D12.776.157.057.012 Caveolin 2 1
D12.776.157.057.014 Cortactin 1
D12.776.157.057.016 Crk-Associated Substrate Protein 7
D12.776.157.057.018 Death Domain Receptor Signaling Adaptor Proteins 5
D12.776.157.057.023 Discs Large Homolog 1 Protein
D12.776.157.057.028 Dishevelled Proteins 18
D12.776.157.057.039 GRB10 Adaptor Protein
D12.776.157.057.041 GRB2 Adaptor Protein 3
D12.776.157.057.043 GRB7 Adaptor Protein
D12.776.157.057.045 Insulin Receptor Substrate Proteins 6
D12.776.157.057.050 Interferon Regulatory Factors 11
D12.776.157.057.061 Interferon-Stimulated Gene Factor 3
D12.776.157.057.067 Kelch-Like ECH-Associated Protein 1 9
D12.776.157.057.072 Mediator Complex 5
D12.776.157.057.073 mTOR Associated Protein, LST8 Homolog
D12.776.157.057.074 Myeloid Differentiation Factor 88 16
D12.776.157.057.078 Nod Signaling Adaptor Proteins 1
D12.776.157.057.080 Nuclear Receptor Coactivators 6
D12.776.157.057.086 Nuclear Receptor Interacting Protein 1 3
D12.776.157.057.092 Paxillin 5
D12.776.157.057.110 PII Nitrogen Regulatory Proteins
D12.776.157.057.124 Protein Inhibitors of Activated STAT 3
D12.776.157.057.139 Proto-Oncogene Proteins c-crk 1
D12.776.157.057.144 Proto-Oncogene Proteins c-vav 4
D12.776.157.057.150 Rabphilin-3A
D12.776.157.057.155 Rapamycin-Insensitive Companion of mTOR Protein 2
D12.776.157.057.157 Regulatory-Associated Protein of mTOR
D12.776.157.057.158 Retinoblastoma Binding Proteins 3
D12.776.157.057.160 Sequestosome-1 Protein 3
D12.776.157.057.162 Shc Signaling Adaptor Proteins
D12.776.157.057.166 Signaling Lymphocytic Activation Molecule Associated Protein
D12.776.157.057.170 Smad Proteins 14
D12.776.157.057.186 STAT Transcription Factors 23
D12.776.157.057.249 Suppressor of Cytokine Signaling Proteins 11
D12.776.157.057.374 Syntenins 2
D12.776.157.057.437 Transcriptional Coactivator with PDZ-Binding Motif Proteins 1
D12.776.157.057.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 4
D12.776.157.057.750 YAP-Signaling Proteins 5
D12.776.220 Cytoskeletal Proteins 97
D12.776.220.525 Microfilament Proteins 52
D12.776.220.525.032 Actin Capping Proteins 1
D12.776.220.525.212 Actin Depolymerizing Factors 5
D12.776.220.525.246 Actin-Related Protein 2-3 Complex 4
D12.776.220.525.250 Actinin 11
D12.776.220.525.255 Actins 292
D12.776.220.525.268 Calponins 1
D12.776.220.525.281 Cortactin 1
D12.776.220.525.315 Filamins 4
D12.776.220.525.333 Formins 2
D12.776.220.525.350 Gelsolin 5
D12.776.220.525.475 Myosins 132
D12.776.220.525.556 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.220.525.637 Profilins 10
D12.776.220.525.719 Tensins 1
D12.776.220.525.800 Tropomyosin 23
D12.776.220.525.825 Troponin 263
D12.776.220.525.869 Vasodilator-Stimulated Phosphoprotein
D12.776.220.525.912 Wiskott-Aldrich Syndrome Protein Family 2
D12.776.476 Intracellular Signaling Peptides and Proteins 174
D12.776.476.024 Adaptor Proteins, Signal Transducing 176
D12.776.476.024.034 5-Lipoxygenase-Activating Proteins 1
D12.776.476.024.050 14-3-3 Proteins 75
D12.776.476.024.069 A Kinase Anchor Proteins 1
D12.776.476.024.087 Angiomotins 1
D12.776.476.024.104 Arrestins 6
D12.776.476.024.139 CARD Signaling Adaptor Proteins 7
D12.776.476.024.280 Caveolin 1 14
D12.776.476.024.295 Caveolin 2 1
D12.776.476.024.311 Cortactin 1
D12.776.476.024.316 Crk-Associated Substrate Protein 7
D12.776.476.024.320 Death Domain Receptor Signaling Adaptor Proteins 5
D12.776.476.024.325 Discs Large Homolog 1 Protein
D12.776.476.024.330 Dishevelled Proteins 18
D12.776.476.024.377 GRB2 Adaptor Protein 3
D12.776.476.024.379 GRB7 Adaptor Protein
D12.776.476.024.380 GRB10 Adaptor Protein
D12.776.476.024.381 Homer Scaffolding Proteins 1
D12.776.476.024.382 Insulin Receptor Substrate Proteins 6
D12.776.476.024.385 Interferon Regulatory Factors 11
D12.776.476.024.386 Interferon-Stimulated Gene Factor 3
D12.776.476.024.387 Kelch-Like ECH-Associated Protein 1 9
D12.776.476.024.388 Mediator Complex 5
D12.776.476.024.389 mTOR Associated Protein, LST8 Homolog
D12.776.476.024.390 Myeloid Differentiation Factor 88 16
D12.776.476.024.391 Nod Signaling Adaptor Proteins 1
D12.776.476.024.394 Nuclear Receptor Coactivators 6
D12.776.476.024.396 Nuclear Receptor Interacting Protein 1 3
D12.776.476.024.397 Paxillin 5
D12.776.476.024.400 PII Nitrogen Regulatory Proteins
D12.776.476.024.402 Protein Inhibitors of Activated STAT 3
D12.776.476.024.404 Proto-Oncogene Proteins c-crk 1
D12.776.476.024.407 Proto-Oncogene Proteins c-vav 4
D12.776.476.024.409 Rabphilin-3A
D12.776.476.024.411 Rapamycin-Insensitive Companion of mTOR Protein 2
D12.776.476.024.414 Receptor Activity-Modifying Proteins 1
D12.776.476.024.419 Regulatory-Associated Protein of mTOR
D12.776.476.024.420 Retinoblastoma Binding Proteins 3
D12.776.476.024.422 Sequestosome-1 Protein 3
D12.776.476.024.424 Shc Signaling Adaptor Proteins
D12.776.476.024.426 Signaling Lymphocytic Activation Molecule Associated Protein
D12.776.476.024.428 Smad Proteins 14
D12.776.476.024.430 STAT Transcription Factors 23
D12.776.476.024.437 Suppressor of Cytokine Signaling Proteins 11
D12.776.476.024.468 Syntenins 2
D12.776.476.024.484 Transcriptional Coactivator with PDZ-Binding Motif Proteins 1
D12.776.476.024.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 4
D12.776.476.024.750 YAP-Signaling Proteins 5
D12.776.744 Phosphoproteins 187
D12.776.744.049 bcl-Associated Death Protein 2
D12.776.744.100 BRCA1 Protein 101
D12.776.744.150 Caseins 80
D12.776.744.287 Caveolin 1 14
D12.776.744.356 Caveolin 2 1
D12.776.744.360 CDC2 Protein Kinase 36
D12.776.744.390 Cortactin 1
D12.776.744.425 Crk-Associated Substrate Protein 7
D12.776.744.459 Dopamine and cAMP-Regulated Phosphoprotein 32 3
D12.776.744.476 Fanconi Anemia Complementation Group A Protein 1
D12.776.744.484 Fanconi Anemia Complementation Group D2 Protein 4
D12.776.744.488 Fanconi Anemia Complementation Group G Protein 2
D12.776.744.493 Focal Adhesion Kinase 1 3
D12.776.744.527 Integrin-Binding Sialoprotein 1
D12.776.744.562 Interferon Regulatory Factor-3 3
D12.776.744.631 Interferon Regulatory Factor-7 3
D12.776.744.665 Paxillin 5
D12.776.744.700 Phosvitin
D12.776.744.736 Plectin 8
D12.776.744.741 Smad Proteins, Receptor-Regulated 1
D12.776.744.747 Retinoblastoma-Like Protein p107 4
D12.776.744.755 Retinoblastoma-Like Protein p130 5
D12.776.744.770 Retinoblastoma Protein 52
D12.776.744.772 Stathmin 4
D12.776.744.840 Synapsins 2
D12.776.744.845 Tumor Suppressor Protein p53 755
D12.776.744.925 Vitellogenins 20
D12.776.744.962 Zyxin

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