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Austrian Cluster of Tissue Regenerati... 1 Center for Biotechnology and Biomedic... 1 Christian Doppler Laboratory for Skin... 1 Department of Bioinformatics NUTRIM S... 1 Department of Dermatology Faculty of ... 1 Department of Dermatology Medical Uni... 1 Department of Metabolic Diseases Univ... 1 Faculty of Pharmacy in Hradec Králové... 1 Institute of Bioanalytical Chemistry ... 1 Institute of Chemical Technologies an... 1 Maastricht Centre for Systems Biology... 1
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Austrian Cluster of Tissue Regenerati... 1 Center for Biotechnology and Biomedic... 1 Christian Doppler Laboratory for Skin... 1 Department of Bioinformatics NUTRIM S... 1 Department of Dermatology Faculty of ... 1 Department of Dermatology Medical Uni... 1 Department of Metabolic Diseases Univ... 1 Faculty of Pharmacy in Hradec Králové... 1 Institute of Bioanalytical Chemistry ... 1 Institute of Chemical Technologies an... 1 Maastricht Centre for Systems Biology... 1
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Sochorová, Michaela
Autor Sochorová, Michaela Department of Dermatology, Medical University of Vienna, Vienna, Austria Christian Doppler Laboratory for Skin Multimodal Analytical Imaging of Aging and Senescence (SKINMAGINE), Medical University of Vienna, Vienna, Austria Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic
- Vávrová, Kateřina
- Fedorova, Maria
- Ni, Zhixu
- Slenter, Denise
- Kutmon, Martina
- Willighagen, Egon L
- Letsiou, Sophia
- Töröcsik, Daniel
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Marchetti-Deschmann, Martina
Autor Marchetti-Deschmann, Martina Christian Doppler Laboratory for Skin Multimodal Analytical Imaging of Aging and Senescence (SKINMAGINE), Medical University of Vienna, Vienna, Austria Institute of Chemical Technologies and Analytics, TU Wien (Vienna University of Technology), Vienna, Austria Austrian Cluster of Tissue Regeneration, Vienna, Austria
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PubMed
34924150
DOI
10.1016/j.jid.2021.09.017
Knihovny.cz E-zdroje
Although lipids are crucial molecules for cell structure, metabolism, and signaling in most organs, they have additional specific functions in the skin. Lipids are required for the maintenance and regulation of the epidermal barrier, physical properties of the skin, and defense against microbes. Analysis of the lipidome-the totality of lipids-is of similar complexity to those of proteomics or other omics, with lipid structures ranging from simple, linear, to highly complex structures. In addition, the ordering and chemical modifications of lipids have consequences on their biological function, especially in the skin. Recent advances in analytic capability (usually with mass spectrometry), bioinformatic processing, and integration with other dermatological big data have allowed researchers to increasingly understand the roles of specific lipid species in skin biology. In this paper, we review the techniques used to analyze skin lipidomics and epilipidomics.
- MeSH
- big data MeSH
- biomedicínský výzkum MeSH
- epigeneze genetická MeSH
- hmotnostní spektrometrie MeSH
- kůže metabolismus patologie MeSH
- lidé MeSH
- lipidomika metody MeSH
- metabolismus lipidů MeSH
- výpočetní biologie MeSH
- zvířata MeSH
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- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
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