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Autor
Abramowicz, Pawel 1 Baptista, Fátima 1 Beaudart, Charlotte 1 Bhattoa, Harjit Pal 1 Bruyère, Olivier 1 Drey, Michael 1 Dzhus, Marta 1 Emin, Gyulnaz 1 Erdoğan, Tuğba 1 Fernandez-Garrido, Julio 1 Fábrega-Cuadros, Raquel 1 Gasparik, Andrea-Ildiko 1 Geerinck, Anton 1 Hiligsmann, Mickael 1 Iacob, Speranta 1 Kilaitė, Justina 1 Kumar, Prabal 1 Laurindo, Lucas Fornari 1 Lee, Shu-Chun 1 Lou, Vivian W Q 1
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Pracoviště
Bogomolets National Medical Universit... 1 CUHK Jockey Club Institute of Ageing ... 1 Carol Davila University of Medicine a... 1 Clinic of Internal Diseases Family Me... 1 Departement of Biomedical Sciences Na... 1 Department of Biochemistry and Pharma... 1 Department of Biochemistry and Pharma... 1 Department of Biomedical Sciences Fac... 1 Department of Clinical Nutrition Scho... 1 Department of Geriatric Medicine 1st ... 1 Department of Geriatrics North Wester... 1 Department of Gerontology Federal Uni... 1 Department of Health Sciences Univers... 1 Department of Health Services Researc... 1 Department of Laboratory Medicine Fac... 1 Department of Medicine 4 LMU Universi... 1 Department of Orthopaedic Surgery Inh... 1 Department of Pediatrics Rheumatology... 1 Department of Physiotherapy Manipal C... 1 Department of Physiotherapy School of... 1
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Abramowicz, Pawel 1 Baptista, Fátima 1 Beaudart, Charlotte 1 Bhattoa, Harjit Pal 1 Bruyère, Olivier 1 Drey, Michael 1 Dzhus, Marta 1 Emin, Gyulnaz 1 Erdoğan, Tuğba 1 Fernandez-Garrido, Julio 1 Fábrega-Cuadros, Raquel 1 Gasparik, Andrea-Ildiko 1 Geerinck, Anton 1 Hiligsmann, Mickael 1 Iacob, Speranta 1 Kilaitė, Justina 1 Kumar, Prabal 1 Laurindo, Lucas Fornari 1 Lee, Shu-Chun 1 Lou, Vivian W Q 1
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Pracoviště
Bogomolets National Medical Universit... 1 CUHK Jockey Club Institute of Ageing ... 1 Carol Davila University of Medicine a... 1 Clinic of Internal Diseases Family Me... 1 Departement of Biomedical Sciences Na... 1 Department of Biochemistry and Pharma... 1 Department of Biochemistry and Pharma... 1 Department of Biomedical Sciences Fac... 1 Department of Clinical Nutrition Scho... 1 Department of Geriatric Medicine 1st ... 1 Department of Geriatrics North Wester... 1 Department of Gerontology Federal Uni... 1 Department of Health Sciences Univers... 1 Department of Health Services Researc... 1 Department of Laboratory Medicine Fac... 1 Department of Medicine 4 LMU Universi... 1 Department of Orthopaedic Surgery Inh... 1 Department of Pediatrics Rheumatology... 1 Department of Physiotherapy Manipal C... 1 Department of Physiotherapy School of... 1
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Beaudart, Charlotte
Autor Beaudart, Charlotte Departement of Biomedical Sciences, Namur Research Institute for Life Sciences (NARILIS), Faculty of Medicine, University of Namur, Namur, Belgium WHO Collaborating Centre for Public Health Aspects of Musculo-Skeletal Health and Ageing, Division of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium Department of Health Services Research, University of Maastricht, Maastricht, the Netherlands. Electronic address: charlotte.beaudart@unamur.be
- Tilquin, Noémie
- Abramowicz, Pawel
- Baptista, Fátima
- Peng, Dao Juan
- de Souza Orlandi, Fabiana
- Drey, Michael
- Dzhus, Marta
- Fábrega-Cuadros, Raquel
- Fernandez-Garrido, Julio
Age-related sarcopenia, resulting from a gradual loss in skeletal muscle mass and strength, is pivotal to the increased prevalence of functional limitation among the older adult community. The purpose of this meta-analysis of individual patient data is to investigate the difference in health-related quality of life between sarcopenic individuals and those without the condition using the Sarcopenia Quality of Life (SarQoL) questionnaire. A protocol was published on PROSPERO. Multiple databases and the grey literature were searched until March 2023 for studies reporting quality of life assessed with the SarQoL for patients with and without sarcopenia. Two researchers conducted the systematic review independently. A two-stage meta-analysis was performed. First, crude (mean difference) and adjusted (beta coefficient) effect sizes were calculated within each database; then, a random effect meta-analysis was applied to pool them. Heterogeneity was measured using the Q-test and I2 value. Subgroup analyses were performed to investigate the source of potential heterogeneity. The strength of evidence of this association was assessed using GRADE. From the 413 studies identified, 32 were eventually included, of which 10 were unpublished data studies. Sarcopenic participants displayed significantly reduced health-related quality of life compared with non-sarcopenic individuals (mean difference = -12.32; 95 % CI = [-15.27; -9.37]). The model revealed significant heterogeneity. Subgroup analyses revealed a substantial impact of regions, clinical settings, and diagnostic criteria on the difference in health-related quality of life between sarcopenic and non-sarcopenic individuals. The level of evidence was moderate. This meta-analysis of individual patient data suggested that sarcopenia is associated with lower health-related quality of life measured with SarQoL.
- MeSH
- kvalita života MeSH
- lidé MeSH
- prevalence MeSH
- průzkumy a dotazníky MeSH
- sarkopenie * epidemiologie MeSH
- senioři MeSH
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- lidé MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- metaanalýza MeSH
- přehledy MeSH
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