We investigated the role of prostaglandin E2 in reptilian regeneration. Prostaglandin E2 is known to play a vital role during wound healing and cell proliferation. A significant delay in the rate of growth of regenerate after autotomy was observed when the production of prostaglandin E2 was blocked by usage of specific cyclooxygenase inhibitors as compared to control animals and this delay continued to all the defined stages of regeneration. Therefore, prostaglandin E2 could be one of the essential requirements for a successful process of regeneration.

• MeSH
• cyklooxygenasa 2 biosyntéza   MeSH
• dinoproston antagonisté a inhibitory   fyziologie   MeSH
• inhibitory cyklooxygenasy farmakologie   MeSH
• ještěři fyziologie   MeSH
• ocas fyziologie   účinky léků   MeSH
• pyrazoly farmakologie   MeSH
• pyridiny farmakologie   MeSH
• regenerace fyziologie   účinky léků   MeSH
• sulfonamidy farmakologie   MeSH
• sulfony farmakologie   MeSH
• zvířata MeSH
• Check Tag
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• zvířata MeSH