Lamins are the best characterized cytoskeletal components of the cell nucleus that help to maintain the nuclear shape and participate in diverse nuclear processes including replication or transcription. Nuclear actin is now widely accepted to be another cytoskeletal protein present in the nucleus that fulfills important functions in the gene expression. Some viruses replicating in the nucleus evolved the ability to interact with and probably utilize nuclear actin for their replication, e.g., for the assembly and transport of capsids or mRNA export. On the other hand, lamins play a role in the propagation of other viruses since nuclear lamina may represent a barrier for virions entering or escaping the nucleus. This review will summarize the current knowledge about the roles of nuclear actin and lamins in viral infections.
- MeSH
- aktiny metabolismus MeSH
- Baculoviridae metabolismus patogenita MeSH
- buněčné jádro metabolismus virologie MeSH
- cytoskelet MeSH
- Herpesviridae metabolismus patogenita MeSH
- herpetické infekce metabolismus patologie virologie MeSH
- laminy metabolismus MeSH
- lidé MeSH
- replikace viru MeSH
- Retroviridae metabolismus patogenita MeSH
- retrovirové infekce metabolismus patologie virologie MeSH
- sestavení viru MeSH
- virové nemoci metabolismus virologie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
