Orthopedic implants heal well without complications in most patients but fail for unclear reasons in some individuals. This study determined the relevance of metal hypersensitivity in patients with failed orthopedic implants and those requiring orthopedic implant surgery. The study included 35 patients with failed orthopedic implants and 15 subjects scheduled for orthopedic implant surgery. The production of selected pro-inflammatory cytokines was measured in patients with failed orthopedic implants. Metal hypersensitivity was measured in all subjects using the MELISA® test. Of common metals in orthopedic alloys, the patients with failed orthopedic implants responded most frequently to nickel, chromium, titanium, iron, and molybdenum. Hypersensitivity to metals found in implants was measured in 40% of patients with failed implants. The study also showed that titanium exposure in patients with titanium hypersensitivity might lead to implant failure. Metal hypersensitivity testing should be offered to patients before surgery to minimize the risk of implant failure.
- MeSH
- alergie * MeSH
- cytokiny MeSH
- kovy škodlivé účinky MeSH
- lidé MeSH
- protézy a implantáty škodlivé účinky MeSH
- studie případů a kontrol MeSH
- titan * škodlivé účinky MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
OBJECTIVES: To show selected findings from the Global Youth Tobacco Survey (GYTS) conducted in Czech Republic, Hungary, Poland and Slovakia. METHODS: Representative sample of 16918 school children aged 13-15 years; data were obtained through uniform questionnaires. The fieldwork was conducted in 2002 and 2003. RESULTS: Age at initiation of smoking was particularly earlier in Czech Republic, Poland, and Slovakia than in Hungary. Over one third of the students reported current cigarette smoking in Czech Republic (34.9%) and Hungary (33.5%) compared to about one-fourth in Slovakia (24.3%) and Poland (23.3%). Among current smokers, about two thirds in Slovakia (64.0%) desired to stop smoking, while only one third in Hungary (36.7%). The prevalence of current cigarette smoking was similar between genders. DISCUSSION: Smoking prevalence in these countries is considerably higher than worldwide data. Women's smoking could be an important public health problem in the future. Repeated surveys could show trends and give a clearer picture of the epidemiological situation.
- MeSH
- chování mladistvých * MeSH
- kouření epidemiologie MeSH
- lidé MeSH
- mladiství MeSH
- odvykání kouření statistika a číselné údaje MeSH
- prevalence MeSH
- prevence kouření MeSH
- průzkumy a dotazníky MeSH
- sběr dat MeSH
- sexuální faktory MeSH
- věkové faktory MeSH
- Check Tag
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Geografické názvy
- Česká republika MeSH
- Maďarsko epidemiologie MeSH
- Polsko epidemiologie MeSH
- Slovenská republika epidemiologie MeSH
